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merck millipore,默克密理博,118415,ADP-HPD, Dihydrate, Ammonium Salt - Calbiochem
产品名称：ADP-HPD, Dihydrate, Ammonium Salt - Calbiochem
产品型号：118415
An amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC₅₀ = 120 nM).
merck millipore,默克密理博,118415,ADP-HPD, Dihydrate, Ammonium Salt - Calbiochem
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重要规格表
经验配方 C₁₅H₂₃N₆O₁₂P₂ · NH₄ · 2H₂O 描述 概述 An amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC50 = 120 nM). Does not affect the activities of either poly(ADP-ribose) polymerase (PARP) or NAD:arginine mono(ADP-ribosyl)-transferase A even at 1 mM concentration. Also acts as an inhibitor of NAD glycohydrolase from Bungarus fasciatus venom at much higher concentrations (IC50 = 260 µM). Note: 1 set = 5 x 60 µg. Note: 1 set = 5 x 60 µg 产品目录编号 118415 品牌系列 Calbiochem®
同义词 Adenosine 5ʹ-diphosphate (Hydroxymethyl)pyrrolidinediol, NH₄ 参考 参考 Vispe, S., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 9886.
Slama, J.T., et al. 1995. J. Med. Chem. 38, 389.
Slama, J.T., et al. 1995. J. Med. Chem. 38, 4332.产品信息 具有ATP竞争性 N 形式 White lyophilized solid Hill配方 C₁₅H₂₃N₆O₁₂P₂ · NH₄ · 2H₂O 化学配方 C₁₅H₂₃N₆O₁₂P₂ · NH₄ · 2H₂O Molar Mass 595.4 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 PARG 主靶IC50 120 nM against poly(ADP-ribose) glycohydrolase (PARG) 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 溶解度 H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 1 week at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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