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merck millipore,默克密理博,207001,Calcineurin Autoinhibitory Peptide, Cell-permeable - Calbiochem
产品名称：Calcineurin Autoinhibitory Peptide, Cell-permeable - Calbiochem
产品型号：207001
The Calcineurin Autoinhibitory Peptide, Cell-permeable controls the biological activity of Mn2+-stimulated calcineurin activity. This small molecule/inhibitor is primarily used for Phosphorylation & D More>>
merck millipore,默克密理博,207001,Calcineurin Autoinhibitory Peptide, Cell-permeable - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₃₇H₂₅₁N₇₁O₃₄S₂ 描述 概述 A cell-permeable peptide that is composed of the calcineurin (CaN) autoinhibitory domain (AID) fused to a poly-arginine-based protein transduction domain (11R) and acts as an inhibitor of CaN phosphatase activity. Blocks CaN-dependent NFAT nuclear translocation and NFAT promoter activity in neurons. Protects neuronal cells from glutamate-induced cell death. 产品目录编号 207001 品牌系列 Calbiochem®
同义词 11R-CaN-AID, Ac-RRRRRRRRRRRGGGRMAPPRRDAMPSDA-NH₂ 参考 参考 Terada, H., et al. 2003. J. Neurochem. 87, 1145. 产品信息 具有ATP竞争性 N 形式 White lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₁₃₇H₂₅₁N₇₁O₃₄S₂ 化学配方 C₁₃₇H₂₅₁N₇₁O₃₄S₂ Molar Mass 3501.1 吸湿 Hygroscopic
肽序列 Ac-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Gly-Arg-Met-Ala-Pro-Pro-Arg-Arg-Asp-Ala-Met-Pro-Ser-Asp-Ala-NH₂ 可逆 N 生物信息 主靶 Blocks CaN-dependent NFAT nuclear translocation 纯度 ≥98% by HPLC 理化信息 细胞可渗透 Y 溶解度 H₂O 肽序列 Ac-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Gly-Arg-Met-Ala-Pro-Pro-Arg-Arg-Asp-Ala-Met-Pro-Ser-Asp-Ala-NH₂ 储存和货运信息 货运代码 Blue Ice Only
毒性 Carcinogenic / Teratogenic
储存 -20°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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