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品种反应性 主要应用 宿主 格式 抗体类型 R WB M Ascites Monoclonal Antibody 描述 产品目录编号 MAB5576 商名 - Chemicon
描述 Anti-NMDAR2C Antibody 背景信息 NMDA receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B or NR2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2B may be a candidate gene for the neurodegenerative disorder dentato-rubro-pallidoluysian atrophy (DRPLA). Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage dependent Mg2+ blockade and high Ca2+ permeability. The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer's disease and also epilepsy and ischemic neuronal cell death. 产品信息 格式 Ascites 控制 - Tested on rat brain lysate
演示 Mouse ascites IgG1k in buffer containing 0.05% sodium azide. 应用 应用 This Anti-NMDAR2C Antibody is validated for use in WB for the detection of NMDAR2C. 主要应用 - Western Blotting
应用说明 Rat Brain lysate was resolved by electrophoresis, transferred to PVDF and probed with anti-NMDAR2C, clone G218B5 (1:1000 dilution). Proteins were visualized using Goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system.
生物信息 免疫原品种 Recombinant protein with His-tag from the C-Terminus. 宿主 Mouse 特异性 Antibody recognizes C-Terminus of NMDAR2 同种型 IgG1κ 品种反应性 Rat 抗体类型 Monoclonal Antibody UniProt编号 - NP_000826
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. 包装信息 数量 100 µL
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