• merck millipore,默克密理博,204896,Complement C8, Human
  • merck millipore,默克密理博,204896,Complement C8, Human

    产品名称:Complement C8, Human
    产品型号:204896


    merck millipore,默克密理博,204896,Complement C8, Human

  • 产品介绍
  • merck millipore,默克密理博,204896,Complement C8, Human

    描述
    概述 Native, human C8 complement component. Glycoprotein composed of three non-identical subunits of M.W. 64 kDa (α), 64 kDa (β), and 22 kDa (γ). Present in normal human serum at 55 µg/ml. On activation of complement via either the classical or alternative pathway, C5 is cleaved into C5a and C5b fragments. The nascent C5b fragment binds to C6, C7, and C8 resulting in formation of the C5b-8 complex on target surfaces. Each membrane-bound, hydrophobic C5b-8 complex combines with three to six C9 molecules to complete the assembly of the lytic C5b-9 complement membrane attack complex (MAC).
    产品目录编号 204896
    品牌系列 Calbiochem®
    参考
    参考 Steckel, E.W., et al. 1980. J. Biol. Chem. 255, 11997.
    Petersen, B.H., et al. 1976. J. Clin. Invest. 57, 283.
    产品信息
    CAS号 80295-58-5
    形式 Liquid
    配方 In PBS, pH 7.2.
    Molar Mass 150000
    生物信息
    纯度 ≥85% by SDS-PAGE
    来源 Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
    特异活性 ≥150,000 C₈H₅0 units/mg
    浓缩标签 Please refer to vial label for lot-specific concentration
    理化信息
    污染物 IgG, IgA, IgM, albumin, C3, C4, C7, C9: ≤trace amounts
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Standard Handling
    储存 ≤ -70°C
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).

    merck millipore,默克密理博,204896,Complement C8, Human

上一件merck millipore产品:merck millipore,默克密理博,118501,ATM/ATR Kinase Inhibitor - CAS 905973-89-9 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,CC083,Bovine Collagen Type IV



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