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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC837 描述 Anti-ARC Antibody Alternate Names - ARC
- Nucleolar protein 3
- Apoptosis repressor with CARD
- Muscle-enriched cytoplasmic protein
- Myp
- Nucleolar protein of 30 kDa
- Nop30
背景信息 Nucleolar protein 3 (NOL3), also known as Apoptosis repressor with CARD or Muscle-enriched cytoplasmic protein (Myp) or Nucleolar protein of 30 kDa (Nop30) and encoded by the gene name NOL3 or ARC contains one CARD domain. Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and –8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-ARC Antibody detects level of ARC & has been published & validated for use in ARC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected ARC in human heart and skeletal muscle tissues. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to amino acids 191-208 at the C-terminus of human ARC. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - NOP
- NOL3
- ARC
纯化方法 Antigen Affinity purified UniProt编号 - O60936
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa, KB, and A549 cell lysates.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected ARC in HeLa, KB, and A549 cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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