merck millipore,默克密理愽
  • merck millipore,默克密理博,190080,AY 9944 - CAS 366-93-8 - Calbiochem

  • merck millipore,默克密理博,190080,AY 9944 - CAS 366-93-8 - Calbiochem

    产品名称：AY 9944 - CAS 366-93-8 - Calbiochem
    产品型号：190080
    A cell-permeable amphiphilic diamine that blocks cholesterol biosynthesis and its esterification.

    merck millipore,默克密理博,190080,AY 9944 - CAS 366-93-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,190080,AY 9944 - CAS 366-93-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₂H₂₈Cl₂N₂ • 2HCl366-93-8
    描述
    概述 A cell-permeable amphiphilic diamine that blocks cholesterol biosynthesis and its esterification. Specifically blocks 7-dehydrocholesterol reductase (Δ7-sterol reductase) activity with IC50= 13 nM. Important tool in Sonic Hedgehog signaling and teratogenicity studies. Also reported to induce a rapid and irreversible reduction in Acidic-Sphingomyelinase activity in fibroblasts.
    产品目录编号 190080
    品牌系列 Calbiochem®
    同义词 trans-1,4-bis(2-Chlorobenzylaminomethyl)cyclohexane, 2HCl, Shh Signaling Antagonist IV
    参考
    参考 Gofflot, F., et al. 2001. Dev. Dyn. 220, 99.
    Cooper, M.K., et al. 1998. Science 280, 1603.
    Incardona, J.P., et al. 1998. Development 125, 3553.
    Moebius, F.F., et al. 1998. Proc. Natl. Acad. Sci. USA95, 1899.
    Yoshida, Y. 1985. J. Biochem. 98, 1669.
    Kraml, M., et al. 1964. Biochem. Biophys. Res. Commun. 15, 455.
    产品信息
    CAS号 366-93-8
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₂H₂₈Cl₂N₂ • 2HCl
    化学配方 C₂₂H₂₈Cl₂N₂ • 2HCl
    Molar Mass 464.3
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 7-dehydrocholesterol reductase (δ7-sterol reductase)
    主靶IC50 13 nM in blocking 7-dehydrocholesterol reductase (δ7-sterol reductase) activity
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or H₂O
    GHS安全信息
    RTECS GU7025000
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful & Carcinogenic / Teratogenic
    储存 +2°C to +8°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,190080,AY 9944 - CAS 366-93-8 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,SF-1522,CELF1; Human, Cyanine 5 RNA Detection Probe,SmartFlare
下一件merck millipore产品：merck millipore,默克密理博,05-684,Anti-dimethyl-Histone H3 (Lys4) Antibody, clone RR302


相关产品

merck millipore,默克密理博,MAB1982,Anti-Integrin α6 Antibody, clone MA6 merck millipore,默克密理博,MAB1982,Anti-Integrin α6 Antibody, clone MA6

merck millipore,默克密理博,09-754,Anti-c-Jun Antibody merck millipore,默克密理博,09-754,Anti-c-Jun Antibody

merck millipore,默克密理博,440206,LY 294002, 4ʹ-NH₂ - CAS 942289-87-4 - Calbiochem merck millipore,默克密理博,440206,LY 294002, 4ʹ-NH₂ - CAS 942289-87-4 - Calbiochem

merck millipore,默克密理博,506350,Pam₃Cys-Ser-(Lys)₄, Hydrochloride merck millipore,默克密理博,506350,Pam₃Cys-Ser-(Lys)₄, Hydrochloride

merck millipore,默克密理博,SF-1522,CELF1; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1522,CELF1; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,05-684,Anti-dimethyl-Histone H3 (Lys4) Antibody, clone RR302 merck millipore,默克密理博,05-684,Anti-dimethyl-Histone H3 (Lys4) Antibody, clone RR302

merck millipore,默克密理博,554715,Retro-2 - Calbiochem merck millipore,默克密理博,554715,Retro-2 - Calbiochem

merck millipore,默克密理博,559309,PhosphoDetect™ Anti-SAPK/JNK (pThr¹⁸³, Tyr¹⁸⁵) Rabbit pAb merck millipore,默克密理博,559309,PhosphoDetect™ Anti-SAPK/JNK (pThr¹⁸³, Tyr¹⁸⁵) Rabbit pAb

merck millipore,默克密理博,AB3887,Anti-Cortactin Antibody merck millipore,默克密理博,AB3887,Anti-Cortactin Antibody

merck millipore,默克密理博,05-466,Anti-GRK 4-6 Antibody, clone A16/17 merck millipore,默克密理博,05-466,Anti-GRK 4-6 Antibody, clone A16/17


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部