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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB M Purified Monoclonal Antibody 描述 产品目录编号 05-466 品牌系列 Upstate
商名 - Upstate
描述 Anti-GRK 4-6 Antibody, clone A16/17 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15 NaCl with 0.05% sodium azide 应用 应用 Anti-GRK 4-6 Antibody, clone A16/17 detects level of GRK 4-6 & has been published & validated for use in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 GST fusion protein corresponding to residues 463-590 of bovine GRK 5 克隆 clone A16/17 宿主 Mouse 特异性 GRK 4, GRK 5 and GRK 6 同种型 IgG1κ 品种反应性 RatHumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_019497
Entrez基因汇总 This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. 基因符号 - ITI1
- GRK4
- GRK4a
- IT11
- GPRK4
- GPRK2L
纯化方法 Ammonium sulfate precipitation UniProt编号 - P32298
UniProt汇总 FUNCTION: SwissProt: P32298 # Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin.
SIZE: 578 amino acids; 66583 Da
TISSUE SPECIFICITY: Testis, and in a lower extent in other tissues including brain cortex and striatum.
SIMILARITY: SwissProt: P32298 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 RGS domain.产品使用声明 质量保证 routinely evaluated by immunoblot on murine 3T3/A31 RIPA lysate or human K562 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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