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主要应用 HMT 描述 产品目录编号 17-330 品牌系列 Upstate
商名 - Upstate
描述 Histone Methyltransferase Assay Reagent Kit 概述 Accessory reagent kit for the analysis of histone methyltransferase activity. 产品信息 部件 - P81 Phosphocellulose Squares (Cat.# 20-134)
- 5X HMTase Assay Buffer
- Core histones
应用 应用 Accessory reagent kit for the analysis of histone methyltransferase activity. 主要应用 - Histone Methyltransferase Assay (HMT)
生物信息 Entrez基因编号 - NM_006895.2
- NM_001024074.1
- NM_001024075.1
Entrez基因汇总 In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. 基因符号 - HNMT-S1
- HNMT
- HMT
- HNMT-S2
UniProt编号 - P50135
UniProt汇总 FUNCTION: SwissProt: P50135 # Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
SIZE: 292 amino acids; 33295 Da
SUBUNIT: Monomer.
SUBCELLULAR LOCATION: Cytoplasm.
SIMILARITY: SwissProt: P50135 ## Belongs to the methyltransferase superfamily. HNMT family.产品使用声明 质量保证 Routinely evaluated by methylating core histones with PRMT1, active (14-474). 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 1 kit 包装 Kit capacity: 100 assays
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