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merck millipore,默克密理博,MABE579,Anti-USP22, clone EPR4352(2), Rabbit Monoclonal Antibody
产品名称:Anti-USP22, clone EPR4352(2), Rabbit Monoclonal Antibody
产品型号:MABE579
This Anti-USP22, clone EPR4352(2), Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunocytochemistry and Flow Cytometry for the detection of USP22.
merck millipore,默克密理博,MABE579,Anti-USP22, clone EPR4352(2), Rabbit Monoclonal Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC, WB, ICC Rb Unpurified Monoclonal Antibody 描述 产品目录编号 MABE579 描述 Anti-USP22, clone EPR4352(2), Rabbit Monoclonal Antibody Alternate Names - USP22
- Ubiquitin carboxyl-terminal hydrolase 22
- Deubiquitinating enzyme 22
- Ubiquitin thioesterase 22
- Ubiquitin-specific-processing protease 22
背景信息 Ubiquitin carboxyl-terminal hydrolase 22, also known as Deubiquitinating enzyme 22 or Ubiquitin thioesterase 22 or Ubiquitin-specific-processing protease 22, and encoded by the gene name USP22 or USP3L, belongs to a large family of proteins with ubiquitin hydrolase activity. USP22 catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. USP22 is a death-from-cancer signature and a subunit of the hSAGA coactivator complex. USP22 is recruited to specific promoters by activators such as MYC, where it is required for transcription. Moreover, USP22 is required for nuclear receptor-mediated transactivation and cell cycle progression. USP22 is expressed in various tissues including heart and skeletal muscle, with low levels found in lung and liver. 产品信息 格式 Unpurified 演示 Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol. 应用 应用 This Anti-USP22, clone EPR4352(2), Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunocytochemistry and Flow Cytometry for the detection of USP22. 主要应用 - Flow Cytometry
- Western Blotting
- Immunocytochemistry
应用说明 Immunocytochemistry Analysis: A 1:200 dilution from a representative lot detected USP22 in HeLa cells.
Flow Cytometry Analysis: A 1:10-100 dilution from a representative lot detected USP22 in HeLa cells.
Produced in collaboration with Epitomics™生物信息 免疫原品种 Synthetic peptide corresponding to human USP22. 克隆 EPR4352(2) 浓缩 Please refer to lot specific datasheet. 宿主 Rabbit 同种型 IgG 品种反应性 Human Species Reactivity Note Human 抗体类型 Monoclonal Antibody 基因符号 - USP3L
- USP22
- KIAA1063
纯化方法 Unpurified UniProt编号 - Q9UPT9
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa, human placenta, and HT-1376 lysates.
Western Blotting Analysis: A 1:1,000-5,000 dilution of this antibody detected USP22 in HeLa, human placenta, and HT-1376 lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µL
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