merck millipore,默克密理愽
  • merck millipore,默克密理博,14-763M,Tie2 (R849W) Protein, active, 250 µg

  • merck millipore,默克密理博,14-763M,Tie2 (R849W) Protein, active, 250 µg

    产品名称：Tie2 (R849W) Protein, active, 250 µg
    产品型号：14-763M
    Active, N-terminal 6His-tagged recombinant human Tie2 residues 771-end containing the R849W substitution. For use in Kinase Assays.

    merck millipore,默克密理博,14-763M,Tie2 (R849W) Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-763M,Tie2 (R849W) Protein, active, 250 µg

    描述
    产品目录编号 14-763M
    品牌系列 Upstate
    商名
    • Upstate
    描述 Tie2 (R849W) Protein, active, 250 µg
    概述 N-terminal 6His-tagged recombinant human Tie2 residues 771-end containing the R849W substitution.
    背景信息 The R849W mutation has been reported in dominantly inherited venous malformations. Expression studies in insect and mammalian cells demonstrates that Tie2 R849W has constitutively elevated tyrosine kinase activity compared with wild type. (Morris P.N., et al., Biochem.Biophys.Res.Commun.(2006);346:335-338 and Vikkula M, et al., Cell(1996);87:1181-1190).
    产品信息
    演示 50mM Tris/HCl pH8.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij 35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
    应用
    应用 Active, N-terminal 6His-tagged recombinant human Tie2 residues 771-end containing the R849W substitution. For use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 Expressed by baculovirus in Sf21 insect cell.
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_000459. The recombinant protein contains the amino acid substitutions Q939H and Q940H (native protein coordinates) with respect to GenBank NM_000459, both of these are reported in GenBank BC035514.
    基因符号
    • TIE2
    • TEK
    蛋白靶 Tie2
    纯化方法 Ni2+/NTA-agarose
    靶子系列 TK
    UniProt编号
    • Q02858 (mouse)
    • Q02763
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store -70°C. For maximum recovery of product, centrifuge original vial prior to removing the cap.
    Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C.
    包装信息
    数量 250 µg
    包装 Also available in 10 μg size (cat#14-763) and in bulk (cat# 14-763-K).

    merck millipore,默克密理博,14-763M,Tie2 (R849W) Protein, active, 250 µg

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