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描述 产品目录编号 14-723 品牌系列 Upstate
商名 - Upstate
描述 CaM Kinase IIδ Protein, active, 10 µg 概述 N-terminal 6His-tagged, recombinant, human, full length CaM Kinase IIδ
N-terminal 6His-tagged, recombinant, human, full length CaM Kinase IIδ应用 应用 Active, N-terminal 6His-tagged, recombinant, human, full length CaM Kinase IIδ. For use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 expressed by baculovirus in Sf21 cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_172128.1
- NM_001221.2
- NM_172115.1
- NM_172127.1
Entrez基因汇总 The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Four alternatively spliced transcript variants that encode three different isoforms have been characterized to date. Distinct isoforms of this chain have different expression patterns. 基因符号 - MGC44911
- CAMK2D
- CAMKD
蛋白靶 CaMKIIδ 纯化方法 Ni2+/NTA-agarose 靶子系列 CAMK UniProt编号 - Q13557
UniProt汇总 FUNCTION: SwissProt: Q13557 # CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release.
SIZE: 499 amino acids; 56369 Da
SUBUNIT: CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
TISSUE SPECIFICITY: Expressed in cardiac muscle and skeletal muscle. Isoform Delta 3, isoform Delta 2, isoform Delta 8 and isoform Delta 9 are expressed in cardiac muscle. Isoform Delta 11 is expressed in skeletal muscle.
SIMILARITY: SwissProt: Q13557 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. & Contains 1 protein kinase domain.
MISCELLANEOUS: Expression of CAMK2D is significantly increased in patients suffering from dilated cardiomyopathy.产品使用声明 质量保证 routinely evaluated by phosphorylation of 250μM ZIPtide (Catalog # 12-545) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C from date of shipment 包装信息 数量 10 µg
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