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merck millipore,默克密理博,MABF733,Anti-KLRG1 Antibody (mouse), APC, clone 2F1
产品名称：Anti-KLRG1 Antibody (mouse), APC, clone 2F1
产品型号：MABF733
This golden syrian hamster monoclonal antibody Anti-KLRG1 (mouse), APC, clone 2F1 validated for use in IP & Flow Cytometry for the detection of KLRG1.
merck millipore,默克密理博,MABF733,Anti-KLRG1 Antibody (mouse), APC, clone 2F1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M FC SHm APC Monoclonal Antibody 描述 产品目录编号 MABF733 描述 Anti-KLRG1 Antibody (mouse), APC, clone 2F1 Alternate Names - Mast cell function-associated antigen 2F1
- Killer cell lectin-like receptor subfamily G member 1
背景信息 The 2F1 antibody reacts with mouse KLRG1 (Killer cell Lectin-like Receptor G1). This 30-38 kDa homodimeric receptor may be expressed by activated, mature NK cells and by effector/memory T cells, with potentially different roles in each cell type. KLRG1 can regulate, in an inhibitory fashion, the development and effector functions of NK cells, and is often cited as a senescence or terminal differentiation marker for T cells. Ligands for KLRG1 include members of the cadherin family of adhesion molecules, specifically N-Cadherin, E-Cadherin, and R-Cadherin. These interactions may induce bidirectional, immunosuppressive signaling in both KLRG- and Cadherin-expressing cells. A more recently identified role for KLRG1-Cadherin signaling in tissue organization, e.g. in cardiac angiogenesis, expands the function of these interactions beyond immunosuppression of immune cells. (Bouchentouf et al. 2010. J. Immunol. 185: 7014-7025).The 2F1 antibody may be used as a phenotypic marker for KLRG1 in mouse, frequently in combination with Anti-Mouse CD127 antibody (clone A7R34), for identification of effector T cell populations. 产品信息 格式 APC 演示 Purified Golden Syrian Hamster Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide. 应用 应用 This golden syrian hamster monoclonal antibody Anti-KLRG1 (mouse), APC, clone 2F1 validated for use in IP & Flow Cytometry for the detection of KLRG1. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Immunogen information for this antibody is proprietary information. 克隆 2F1 浓缩 0.2 mg/mL 宿主 Syrian Hamster 同种型 IgG 品种反应性 Mouse 抗体类型 Monoclonal Antibody 基因符号 - Mafa
- Klrg1
纯化方法 Size Exclusion Chromatography UniProt编号 - O88713
产品使用声明 质量保证 The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Flow Cytometry Analysis: 0.06 μg of this antibody detected KLRG1 in one million C57Bl/6 splenocytes.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze. 包装信息 数量 25 µg
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