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描述 产品目录编号 14-699M 品牌系列 Upstate
商名 - Upstate
描述 PAK5 Protein, active, 250 µg 概述 N-terminal 6His-tagged, recombinant, human PAK5, amino acids 425-end. PAK5 is also known as PAK7. 应用 应用 Active, N-terminal 6His-tagged, recombinant, human PAK5, amino acids 425-end. PAK5 is also known as PAK7. For use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 expressed by baculovirus in Sf21 cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_177990.1
- NM_020341.2
Entrez基因汇总 The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. 基因符号 - PAK-7
- PAK7
- PAK-5
- PAK5
- MGC26232
- KIAA1264
蛋白靶 PAK5 纯化方法 Ni2+/NTA-agarose 靶子系列 STE UniProt编号 - Q9P286
UniProt汇总 FUNCTION: SwissProt: Q9P286 # The activated kinase acts on a variety of targets (By similarity).
SIZE: 719 amino acids; 80745 Da
SUBUNIT: Interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1 (By similarity).
TISSUE SPECIFICITY: Predominantly expressed in brain.
PTM: Autophosphorylated when activated by CDC42/p21 (By similarity).
SIMILARITY: SwissProt: Q9P286 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 CRIB domain. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of PAKtide 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C from date of shipment 包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-699) and in bulk (cat# 14-699-K).
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