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描述 产品目录编号 14-695 品牌系列 Upstate
商名 - Upstate
描述 MST3 Protein, active, 10 µg 概述 N-terminal GST-tagged, recombinant, human MST3, amino acids 1-304 应用 应用 Active, N-terminal GST-tagged, recombinant, human MST3, amino acids 1-304, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 expressed by baculovirus in Sf21 cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_003576.3
- NM_001032296.2
Entrez基因汇总 The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM] 基因符号 - STK3
- STK24
- MST3B
- MST3
- MST-3
蛋白靶 MST3 纯化方法 Glutathione agarose affinity chromatography 靶子系列 STE UniProt编号 - Q9Y6E0
UniProt汇总 FUNCTION: SwissProt: Q9Y6E0 # Protein kinase that act on both serine and threonine residues.
COFACTOR: Manganese. Only isoform A requires manganese.
SIZE: 443 amino acids; 49308 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Isoform A is ubiquitous. Isoform B is expressed in brain with high expression in hippocampus and cerebral cortex.
PTM: Autophosphorylated. Isoform B is activated by phosphorylation by PKA.
SIMILARITY: SwissProt: Q9Y6E0 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of PKCtide (Catalog# 12-536) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 stable for 6 months at -70°C from date of shipment 包装信息 数量 10 µg
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