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品种反应性 主要应用 宿主 格式 抗体类型 H, R, M WB Rb Serum Polyclonal Antibody 描述 产品目录编号 07-1459 Replaces 04-1089 描述 Anti-14-3-3 Antibody, 30 & 33 kDa isoforms Alternate Names - tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide 2
- 14-3-3 epsilon
- 14-3-3 protein epsilon
- mitochondrial import stimulation factor L subunit
- protein kinase C inhibitor protein-1
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
- protein, epsilon polypeptide
背景信息 Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers, thus rendering 14-3-3 as a key multifunctional regulatory molecule. 14-3-3 isomers have been implicated in several neurological disorders: for example isoforms gamma, epsilon and beta are expressed in the cerebrospinal fluid of Creutzfeldt-Jakob patients, but not patients suffering from other neurological conditions such as Alzheimer's. 产品信息 格式 Serum 控制 - Jurkat cell lysates
演示 Rabbit serum in liquid containing no preservatives. 应用 应用 Anti-14-3-3 Antibody, 30 & 33 kDa isoforms is an antibody against 14-3-3 for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Synthetic peptide corresponding to rat 14-3-3 epsilon, amino acids 208-244. 表位 a.a 208-244 宿主 Rabbit 特异性 Polyclonal antibody raised in rabbits using a synthetic peptide corresponding to a sequence conserved among 14-3-3 proteins. It reacts with both the 33 kD and 30 kD isoforms of
14-3-3 proteins.品种反应性 HumanRatMouse Species Reactivity Note Proven to react with human, mouse and rat. 抗体类型 Polyclonal Antibody Entrez基因编号 - P62258
基因符号 - FLJ45465
- YWHAE
- KCIP-1
- MDS
- 14-3-3E
- MDCR
纯化方法 Unpurified rabbit serum UniProt编号 - P62258
UniProt汇总 FUNCTION: SwissProt: P62258 # Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
SIZE: 255 amino acids; 29174 Da
SUBUNIT: Homodimer. Interacts with NDEL1 (By similarity). Interacts with HCV core protein.
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
SIMILARITY: SwissProt: P62258 ## Belongs to the 14-3-3 family.产品使用声明 质量保证 Evaluated by Western Blot in Jurkat cell lysates.
Western Blot Analysis: 1:500 dilution of this lot detected 14-3-3 PROTEINS on 10 g of Jurkat lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,14-695,MST3 Protein, active, 10 µg
下一件merck millipore产品：merck millipore,默克密理博,07-2148,Anti-Rho GTPase-activating protein 27 Antibody
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