merck millipore,默克密理愽
  • merck millipore,默克密理博,14-662,Rhotekin, GST fusion protein, 500 µg

  • merck millipore,默克密理博,14-662,Rhotekin, GST fusion protein, 500 µg

    产品名称：Rhotekin, GST fusion protein, 500 µg
    产品型号：14-662
    GST-tagged fusion protein, corresponding to residues 7-89 of mouse Rhotekin Rho Binding Domain. For use in Kinase Assays.

    merck millipore,默克密理博,14-662,Rhotekin, GST fusion protein, 500 µg

  • 产品介绍
  • merck millipore,默克密理博,14-662,Rhotekin, GST fusion protein, 500 µg

    描述
    产品目录编号 14-662
    品牌系列 Upstate
    商名
    • Upstate
    描述 Rhotekin, GST fusion protein, 500 µg
    概述 genbank_accession_number: NM_009106
    应用
    应用 GST-tagged fusion protein, corresponding to residues 7-89 of mouse Rhotekin Rho Binding Domain. For use in Kinase Assays.
    生物信息
    品种 Mouse
    Entrez基因编号
    • NM_033046.2
    • NM_001015055.1
    • NM_001015056.1
    Entrez基因汇总 This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
    基因符号
    • rhotekin
    • RTKN
    • Rhotekin.
    • B5
    UniProt编号
    • Q9BST9
    UniProt汇总 FUNCTION: SwissProt: Q9BST9 # Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures.
    SIZE: 563 amino acids; 62667 Da
    SUBUNIT: Interacts via its C-terminal region with the TAX1BP3 PDZ domain. This interaction facilitates Rho-mediated activation of the c-Fos serum response element (SRE). Interacts with SEPT9. Specifically binds to GTP-bound RHOA, RHOB and RHOC and inhibits their GTPase activity.
    TISSUE SPECIFICITY: Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines.
    SIMILARITY: SwissProt: Q9BST9 ## Contains 1 PH domain. & Contains 1 REM (Hr1) repeat.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 stable 6 months at -20°C from date of shipment
    包装信息
    数量 500 µg

    merck millipore,默克密理博,14-662,Rhotekin, GST fusion protein, 500 µg

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