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描述 产品目录编号 14-619 品牌系列 Upstate
商名 - Upstate
描述 LMPTP-A Protein, 10 µg 概述 GST-tagged, recombinant, full length, human LMPTP-A 应用 应用 GST-tagged, recombinant, full length, human LMPTP-A, for use in Phosphatase Assays. 主要应用 - Phosphatase Assay
生物信息 来源 Expressed in E. coli 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_007099.2
- NM_001040649.1
- NM_004300.2
Entrez基因汇总 The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Three transcript variants encoding distinct isoforms have been identified for this gene. 基因符号 - MGC111030
- ACP1
- HAAP
- LMW-PTP
- LMW-PTPase
- MGC3499
蛋白靶 LMPTP-A 纯化方法 Glutathione agarose affinity chromatography 靶子系列 Tyr phosphatase UniProt编号 - P24666
UniProt汇总 FUNCTION: SwissProt: P24666 # Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.
SIZE: 158 amino acids; 18042 Da
SUBUNIT: Isoform 1 interacts with the SH3 domain of SPTAN1. There is no interaction observed for isoforms 2 or 3.
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: T-lymphocytes express only isoform 2.
SIMILARITY: SwissProt: P24666 ## Belongs to the low molecular weight phosphotyrosine protein phosphatase family.产品使用声明 质量保证 Routinely evaluated by dephosphorylation of DiFMUP 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 10 µg
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