merck millipore,默克密理博,ABC846,Anti-Slc22A17 Antibody

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Merck Millipore 默克密理愽

Replacement Information

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABC846
描述	Anti-Slc22A17 Antibody
Alternate Names	Slc22A17 Solute carrier family 22 member 17 24p3 receptor 24p3R Brain-type organic cation transporter Lipocalin-2 receptor Neutrophil gelatinase-associated lipocalin receptor NgalR
背景信息	Solute carrier family 22 member 17, also known as 24p3 receptor (24p3R) or Brain-type organic cation transporter or Lipocalin-2 receptor or Neutrophil gelatinase-associated lipocalin receptor (NgalR), and encoded by the gene name SLC22A17 or BOCT or BOIT, is a family of organic anion and cation transporters (OATs, OCTs, OCTNs) that are expressed in brain. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.

参考

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

应用
应用	Anti-Slc22A17 Antibody is an antibody against Slc22A17 for use in western blotting & immunofluorescence.
主要应用	Western Blotting
应用说明	Immunofluorescence Analysis: 20 μg/mL from a representative lot detected Slc22A17 in rat kidney tissue.

生物信息
免疫原品种	KLH-conjugated synthetic peptide corresponding to the C-terminus of human Slc22A17.
表位	C-terminus
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	Human
抗体类型	Polyclonal Antibody
基因符号	BOIT SLC22A17 BOCT
纯化方法	Antigen Affinity purified
UniProt编号	Q8WUG5

理化信息

尺寸

材料信息

毒性学信息

GHS安全信息

安全信息

产品使用声明
质量保证	Evaluated by Western Blotting in SK-N-SH cell lysate with and without blocking peptide. Western Blotting Analysis: 1 μg/mL of this antibody detected Slc22A17 in SK-N-SH cell lysate with and without blocking peptide.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

运输信息

补充信息

规格

merck millipore,默克密理博,ABC846,Anti-Slc22A17 Antibody

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