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merck millipore,默克密理博,07-433,Anti-phospho-Ribosomal Protein S6 (Ser235) Antibody
产品名称:Anti-phospho-Ribosomal Protein S6 (Ser235) Antibody
产品型号:07-433
Detect phospho-Ribosomal Protein S6 (Ser235) using this Anti-phospho-Ribosomal Protein S6 (Ser235) Antibody validated for use in WB.
merck millipore,默克密理博,07-433,Anti-phospho-Ribosomal Protein S6 (Ser235) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Xn, Ch, M, R WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-433 品牌系列 Upstate
商名 - Upstate
描述 Anti-phospho-Ribosomal Protein S6 (Ser235) Antibody Alternate Names - RPS6 ribosomal protein S6
- 40S ribosomal protein S6
- RPS6
- Phosphoprotein NP33
产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 Detect phospho-Ribosomal Protein S6 (Ser235) using this Anti-phospho-Ribosomal Protein S6 (Ser235) Antibody validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 peptide corresponding to amino acids 230-242 of human Ribosomal protein S6 表位 phosphorylated Ser235 宿主 Rabbit 特异性 phosphorylated Ribosomal Protein S6 同种型 IgG 品种反应性 XenopusChickenMouseRat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_003161
Entrez基因汇总 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq] 基因符号 - Phosphoprotein NP33
- RPS6
- 40S ribosomal protein S6
- ribosomal protein S6
修改 - Phosphorylation
纯化方法 Protein A purfied UniProt编号 - P62753
UniProt汇总 FUNCTION: SwissProt: P23443 # Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens.
SIZE: 525 amino acids; 59140 Da
SUBUNIT: Interacts with PPP1R9A/neurabin-1 (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell junction, synapse, synaptosome (By similarity).
TISSUE SPECIFICITY: Widely expressed.
SIMILARITY: SwissProt: P23443 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by immunoblot in lysates from serum stimulated 3T3 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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