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品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-2146 描述 Anti-ARHGAP30 Antibody Alternate Names - ARHGAP30
- Rho-type GTPase-activating protein 30
- Rho GTPase-activating protein 30
背景信息 Rho GTPase-activating protein 30 (ARHGAP30) is a GTPase-activating protein (GAP) for RAC1 and RHOA, but not for CDC42. GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. ARHGAP30 contains one Rho-GAP domain and exists as four alternatively spliced isoforms. Conserved in chimpanzee, dog, cow, mouse and rat, ARHGAP30 is among the most neurite-enriched GAPs. One of four single-nucleotide polymorphisms (SNPs) in the promoter area of the USF-1 gene, which is also located within its flanking gene ARHGAP30, is linked to low-density lipoprotein cholesterol levels, incident type 2 diabetes mellitus and increased cardiovascular risk. 产品信息 格式 Affinity Purified 控制 - JURKAT cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Rho GTPase-activating protein 30 using this rabbit polyclonal antibody, Anti-ARHGAP30 Antibody validated for use in western blotting, ICC & IP. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunoprecipitation Assay Analysis: A representative lot detected ARHGAP30 in IP-mass spectrometry (Prof. A. Pawson, Mount Sinai Hospital, Toronto). 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human ARHGAP30. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Other homologies: Mouse (74% sequence homology) and Rat (75% sequence homology). 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001020769
基因符号 - ARHGAP30
纯化方法 Affinity purified UniProt编号 - Q7Z6I6
产品使用声明 质量保证 Evaluated by Western Blotting in JURKAT cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected ARHGAP30 in 10 µg of JURKAT cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,ABC460,Anti-Sec23B Antibody
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