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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Purified Polyclonal Antibody 描述 产品目录编号 06-967 品牌系列 Upstate
商名 - Upstate
描述 Anti-Gab2 Antibody 产品信息 格式 Purified 控制 - HeLa cell lysate
演示 Protein G Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative. 应用 应用 Anti-Gab2 Antibody is an antibody against Gab2 for use in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 GST fusion-protein corresponding to residues 285-676 of human Gab2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Gab2. 同种型 IgG 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_080491
Entrez基因汇总 This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. 基因符号 - pp100
- GAB2
- p97
- KIAA0571
纯化方法 Protein A purfied UniProt编号 - Q9UQC2
UniProt汇总 SIZE: 676 amino acids; 74458 Da
SUBUNIT: Interacts with GRB2, PI-3 kinase and with other SH2- containing proteins.
PTM: Phosphorylated on tyrosine residue(s) by the thrombopoietin receptor (TPOR), stem cell factor receptor (SCFR), and T-cell and B-cell antigen receptors, gp130, IL-2R and IL-3R. & Dephosphorylated by PTPN11.
SIMILARITY: SwissProt: Q9UQC2 ## Belongs to the GAB family. & Contains 1 PH domain.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA lysates from rat L6, Baf3 or Hela cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 200 µg
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