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merck millipore,默克密理博,AB144P-1ML,Anti-Choline Acetyltransferase Antibody
产品名称：Anti-Choline Acetyltransferase Antibody
产品型号：AB144P-1ML
Anti-Choline Acetyltransferase Antibody detects level of Choline Acetyltransferase & has been published & validated for use in IH & WB.
merck millipore,默克密理博,AB144P-1ML,Anti-Choline Acetyltransferase Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Op, Av, Gp, H, M, Mk, R WB, IHC Gt Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB144P-1ML 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Choline Acetyltransferase Antibody Alternate Names - ChAT
产品信息 格式 Affinity Purified 控制 - Rat brain tissue
演示 Affinity Purified immunoglobulin. Liquid in PBS containing 5 mg/mL BSA and 0.2% sodium azide. 应用 应用 Anti-Choline Acetyltransferase Antibody detects level of Choline Acetyltransferase & has been published & validated for use in IH & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunohistochemistry at 1:100. See attached protocol.
Immunoblot at 1:100-1,000. Expected M.W. 68-70 kD.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Human placental enzyme. 宿主 Goat 特异性 Recognizes choline acetyltransferase found in cholinergic neurons in brain and central nervous systems. 品种反应性 OpossumAvianGuinea PigHumanMouseMonkeyRat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_020986.2
- NM_020549.3
- NM_020984.2
- NM_020985.2
Entrez基因汇总 Cholinergic systems are implicated in numerous neurologic functions. Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease. The protein encoded by this gene synthesizes the neurotransmitter acetylcholine. Alternative splice variants have been found that contain alternative 5' untranslated exons. Three of the four described splice variants encode identical 69 kDa proteins while one variant encodes both the 69 kDa and a larger 82 kDa protein. 基因符号 - CMS1A2
- CHAT
- ChAT
- CHOACTase
- CMS1A
纯化方法 Immunoaffinity purified UniProt编号 - P28329
UniProt汇总 FUNCTION: SwissProt: P28329 # Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
SIZE: 748 amino acids; 82568 Da
DISEASE: SwissProt: P28329 # Defects in CHAT are the cause of familial infantile myasthenia gravis 2 (FIMG2) [MIM:254210, 254200]; also known as CMS-EA. FIMG2 patients have myasthenic symptoms since birth or early infancy, negative tests for anti-AChR antibodies, and abrupt episodic crises with increased weakness, bulbar paralysis, and apnea precipitated by undue exertion, fever, or excitement. Inheritance is autosomal recessive.
SIMILARITY: SwissProt: P28329 ## Belongs to the carnitine/choline acetyltransferase family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 1 mL
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