merck millipore,默克密理博,GF144,Epidermal Growth Factor Protein, Human recombinant

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Merck Millipore 默克密理愽

来源	纯度
E.coli	Greater than 98% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of EGF.

描述
产品目录编号	GF144
Replaces	GF001
品牌系列	Chemicon®
商名	Chemicon
描述	Epidermal Growth Factor Protein, Human recombinant
概述	Epidermal Growth Factor (EGF) is a polypeptide growth factor which stimulates the proliferation of a wide range of epidermal and epithelial cells. Human EGF is a 6.2 kDa protein containing 53 amino acid residues.
Alternate Names	EGF

产品信息
演示	Lyophilized from sterile filtered 10 mM Sodium Phosphate, pH 7.5, containing no additives.

应用
应用	The Epidermal Growth Factor (EGF) is a polypeptide growth factor which stimulates the proliferation of a wide range of epidermal & epithelial cells.
应用说明	For most in vitro applications, EGF exerts its biological activity in the concentration range of 0.5 to 25.0 ng/mL. Responding cells are (partial list): Epidermal mesothelial cells.

生物信息
纯度	Greater than 98% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of EGF.
来源	E.coli
特异活性	Human EGF is fully biologically active when compared to standards. The ED50, as determined by its dose-dependent mitogenic activity on BALB/c 3T3 cells, is ≤ 0.1 ng/mL, corresponding to a specific activity of ≥ 1 x 10^7 units/mg.
Entrez基因编号	NM_001963.2
Entrez基因汇总	Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide.
基因符号	urogastrone EGF URG
UniProt编号	P01133
UniProt汇总	FUNCTION: SwissProt: P01133 # EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. SIZE: 1207 amino acids; 133946 Da SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SIMILARITY: SwissProt: P01133 ## Contains 9 EGF-like domains. & Contains 9 LDL-receptor class B repeats.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	The lyophilized EGF, though stable at room temperature, is best stored desiccated at -20°C. Reconstitute with water to a concentration of 0.1 - 1 mg/mL. This solution can be diluted into other buffered solutions and stored at 4°C for 1 week or -20°C for future use. Reconstituted EGF should be maintained at -20°C in undiluted aliquots for up to one year.

包装信息
数量	500 µg

merck millipore,默克密理博,GF144,Epidermal Growth Factor Protein, Human recombinant

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