merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1622,Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6

  • merck millipore,默克密理博,MAB1622,Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6

    产品名称：Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6
    产品型号：MAB1622
    Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6 is an antibody against Spectrin alpha chain (nonerythroid) for use in IH, IP, WB, ChIP.

    merck millipore,默克密理博,MAB1622,Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6

  • 产品介绍
  • merck millipore,默克密理博,MAB1622,Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Ma, Ch, Gp, H, M, R, Rb, PoChIP, IHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1622
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6
    Alternate Names
    • Fodrin α
    • (ALPHA)II-SPECTRIN
    • Alpha-II spectrin
    • Fodrin alpha chain
    • Spectrin, non-erythroid alpha chain
    • non-erythrocytic spectrin alpha
    • spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
    • Fodrin alpha chain
    • Alpha-II spectrin
    • (ALPHA)II-SPECTRIN
    背景信息 Non-erythroid Spectrin, also known as Fodrin, plays a role in stabilizing membrane structures, maintaining cell shape and linking the cytoskeleton to plasma membranes or intracellular vesicles. As one of the primary targets cleaved by activated caspases during apoptosis, the full-length ~240 kDa protein can be cleaved to yield an N-terminal product of ~150 kDa, and C-terminal products of ~120 and ~35 kDa.
    产品信息
    格式 Purified
    控制
    • HeLa cells treated with staurosporine
    演示 Purified mouse monoclonal IgG1 in buffer containing PBS with 1% BSA and 0.09% sodium azide.
    应用
    应用 Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6 is an antibody against Spectrin alpha chain (nonerythroid) for use in IH, IP, WB, ChIP.
    主要应用
    • Chromatin Immunoprecipitation (ChIP)
    • Immunohistochemistry
    • Western Blotting
    不建议的应用
    • Immunohistochemistry (Paraffin)
    应用说明 Immunohistochemistry (IFA):
    A 1:200-1:400 dilution of a previous lot was used in immunohistochemistry.
    Does not work on paraffin sections.

    Optimal working dilutions must be determined by end user.

    Chromatin Immunopreciptiation:
    A previous lot of this antibody was used to immunoprecipitate Spectrin Alpha from chromatin-associated protein extracts derived from normal human, HeLa, FA-A, and transduced FA-A cells (McMahon, L.W., et al. (1999). J. Biological Chem. 274:32904-32908).
    生物信息
    免疫原品种 Chicken red blood cell membranes purified by hypotonic lysis and mechanical enucleation.
    克隆 AA6
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Specific for the 240, 150, and 120 kDa forms of alpha-spectrin/alpha-fodrin molecule of all mammalian nonerythroid cells and chicken alpha-spectrin.
    同种型 IgG1
    品种反应性 MammalsChickenGuinea PigHumanMouseRatRabbitPig
    Species Reactivity Note Chicken, Guinea Pig, Human, Mouse,Pig, Rat, and Rabbit. Wide-mammalian reactivity is expected.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_003127.2
    基因符号
    • SPTA2
    • SPTAN1
    • FLJ44613
    纯化方法 Protein A purfied
    UniProt编号
    • Q13813
    UniProt汇总 FUNCTION: SwissProt: Q13813 # Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
    SIZE:2472 amino acids; 284539 Da
    SUBUNIT: Like erythrocyte spectrin, the spectrin-like proteins are capable of forming dimers which can further associate to tetramers. Interacts with isoform 1 of ACP1.
    SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
    PTM: Phosphorylation of Tyr-1176 decreases sensitivity to cleavage by calpain in vitro (By similarity).
    SIMILARITY: SwissProt: Q13813 ## Belongs to the spectrin family. & Contains 3 EF-hand domains. & Contains 1 SH3 domain. & Contains 23 spectrin repeats.
    产品使用声明
    质量保证 Evaluated by Western Blot on staurosporine-treated HeLa lysates.

    Western Blot Analysis:
    1:500 dilution of this antibody detected N-, C- terminal Spectrin alpha/Fodrin alpha on 10 μg of staurosporine treated HeLa lysates.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 12 months at 2-8°C from date of receipt.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,MAB1622,Anti-Spectrin alpha chain (nonerythroid) Antibody, clone AA6

上一件merck millipore产品：merck millipore,默克密理博,GF144,Epidermal Growth Factor Protein, Human recombinant
下一件merck millipore产品：merck millipore,默克密理博,530070,Pristimerin - CAS 1258-84-0 - Calbiochem


相关产品

merck millipore,默克密理博,539122,Protamine Sulfate, Salmon Milt merck millipore,默克密理博,539122,Protamine Sulfate, Salmon Milt

merck millipore,默克密理博,101008,丙胺酸 merck millipore,默克密理博,101008,丙胺酸

merck millipore,默克密理博,MAB5790,Anti-DSD-1 Antibody, clone 473HD merck millipore,默克密理博,MAB5790,Anti-DSD-1 Antibody, clone 473HD

merck millipore,默克密理博,01-185,VEGF Protein, Human recombinant merck millipore,默克密理博,01-185,VEGF Protein, Human recombinant

merck millipore,默克密理博,GF144,Epidermal Growth Factor Protein, Human recombinant merck millipore,默克密理博,GF144,Epidermal Growth Factor Protein, Human recombinant

merck millipore,默克密理博,530070,Pristimerin - CAS 1258-84-0 - Calbiochem merck millipore,默克密理博,530070,Pristimerin - CAS 1258-84-0 - Calbiochem

merck millipore,默克密理博,ABE24,Anti-BPTF Antibody merck millipore,默克密理博,ABE24,Anti-BPTF Antibody

merck millipore,默克密理博,06-967,Anti-Gab2 Antibody merck millipore,默克密理博,06-967,Anti-Gab2 Antibody

merck millipore,默克密理博,23-029,UbcH5a Protein, active, 50 µg merck millipore,默克密理博,23-029,UbcH5a Protein, active, 50 µg

merck millipore,默克密理博,17-103,Anti-Phosphotyrosine Immunoaffinity Purification Kit merck millipore,默克密理博,17-103,Anti-Phosphotyrosine Immunoaffinity Purification Kit


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部