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merck millipore,默克密理博,05-943,Anti-PAR-1B/MARK2 Antibody, clone 5C12D2
产品名称：Anti-PAR-1B/MARK2 Antibody, clone 5C12D2
产品型号：05-943
This Anti-PAR-1B/MARK2 Antibody, clone 5C12D2 is validated for use in WB for the detection of PAR-1B/MARK2.
merck millipore,默克密理博,05-943,Anti-PAR-1B/MARK2 Antibody, clone 5C12D2
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB M Ascites Monoclonal Antibody 描述 产品目录编号 05-943 品牌系列 Upstate
商名 - Upstate
描述 Anti-PAR-1B/MARK2 Antibody, clone 5C12D2 Alternate Names - MARK2, microtubule affinity-regulating kinase 2
- MARK2
产品信息 格式 Ascites 应用 应用 This Anti-PAR-1B/MARK2 Antibody, clone 5C12D2 is validated for use in WB for the detection of PAR-1B/MARK2. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated, synthetic peptide corresponding to amino acids 288-307 (PDYKDPRRTELMVSMGYTRE) of human PAR-1B/MARK2 克隆 clone 5C12D2 宿主 Mouse 特异性 PAR-1B/MARK2 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_004954, NM_017490
Entrez基因汇总 EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. The human EMK1 was shown to be encoded by a single mRNA ubiquitously expressed. 基因符号 - PAR-1
- MARK2
- MGC99619
- EMK1
纯化方法 Ascites UniProt编号 - Q7KZI7
UniProt汇总 FUNCTION: SwissProt: Q7KZI7 # Role in epithelial morphogenesis. Modulates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery. Essential for the asymmetric development of membrane domains of polarized epithelial cells. One or more isoforms may play a role in graft rejection.
COFACTOR: Magnesium.
SIZE: 788 amino acids; 87911 Da
SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein. Note=Phosphorylated by PRKCZ in polarized epithelial cells, resulting in an interaction with YWHAZ which promotes relocation from the lateral to the apical membrane.
TISSUE SPECIFICITY: High levels of expression in heart, brain, skeletal muscle and pancreas, lower levels observed in lung, liver and kidney.
SIMILARITY: SwissProt: Q7KZI7 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily. & Contains 1 KA1 (kinase-associated) domain. & Contains 1 protein kinase domain. & Contains 1 UBA domain.产品使用声明 质量保证 Routinely evaluated by immunoblot in RIPA lysates from HeLa cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C from date of shipment 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,557514,Ro-31-8425 - CAS 131848-97-0 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,400036,Glucose Transporter Inhibitor IV, WZB117 - CAS 1223397-11-2 - Calbiochem
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