merck millipore,默克密理博,05-636-AF488,Anti-phospho Histone H2A.X (Ser139), clone JBW301, Alexa Fluor 488 Conjugate Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	ICC	M	AlexaFluor®488	Monoclonal Antibody

描述
产品目录编号	05-636-AF488
描述	Anti-phospho Histone H2A.X (Ser139), clone JBW301, Alexa Fluor® 488 Conjugate Antibody
Alternate Names	Histone H2A.X Histone H2AX H2a/x
背景信息	Histone H2A.X is a variant of histone H2A, and is similarly associated with genomic DNA. However, histone is structurally different from other members of the H2A family in possessing a C-terminal tail that contains the Ser139 residue that is phosphorylated in response to breaks in double-stranded DNA. The phosphorylation of H2A.X is a rapid process that is mediated by ATM/ATR proteins.

产品信息
格式	AlexaFluor®488
演示	Purified mouse conjugate in buffer containing PBS, 15 mg/mL BSA, and 0.1% Sodium Azide.

应用
应用	This Anti-phospho Histone H2A.X (Ser139) antibody, clone JBW301, Alexa Fluor® 488 Conjugate is validated for use in ICC for the detection of phospho Histone H2A.X (Ser139).
主要应用	Immunocytochemistry

生物信息
免疫原品种	Linear peptide corresponding to phospho-Histone H2A.X (Ser139).
克隆	JBW301
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
同种型	IgG1
品种反应性	Human
Species Reactivity Note	Human. Predicted to react with Vertebrates based on 100% sequence homology.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP002096
基因符号	H2AX H2AFX
纯化方法	Protein G purified
UniProt编号	P16104

产品使用声明
质量保证	Evaluated by Immunocytochemistry in untreated (negative control) and Staurosporin treated HeLa cells. Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected phospho-Histone H2A.X (Ser139) in Staurosporin treated HeLa cells, and not in untreated HeLa cells.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,05-636-AF488,Anti-phospho Histone H2A.X (Ser139), clone JBW301, Alexa Fluor 488 Conjugate Antibody

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