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经验配方 C₁₃₁H₂₂₄N₃₂O₃₇ 描述 概述 A water soluble, amphiphilic α-helical lipopeptide detergent (LPD) that forms small micelles and effectively mimics lipid bilayers (solubility in PBS ~ 40 mM; micelle MW ~ 23,100; aggregation number ~ 8.1; partial specific volume ~ 0.77 cm3/g). Shown to not only solubilize but also stabilize bacteriorhodopsin, lactose permease and E. coli PagP protein ([LPD] ~ 250 µM and [protein] ~ 22 µM) by forming complexes and precluding aggregation. Useful for NMR and X-ray structural studies of membrane proteins. 产品目录编号 437600 品牌系列 Calbiochem®
同义词 Lipopeptide Detergent-12, Ac-AO(C₁₂)AEAAEKAAKYAAEAAEKAAKAO(C₁₂)A-NH₂ 参考 参考 McGregor, C.L., et al. 2003. Nat. Biotechnol. 21, 171. 产品信息 CMC < 1 μM 形式 White lyophilized 配方 Supplied as a trifluoroacetate salt. Hill配方 C₁₃₁H₂₂₄N₃₂O₃₇ 化学配方 C₁₃₁H₂₂₄N₃₂O₃₇ Molar Mass 2839.4 吸湿 Hygroscopic
肽序列 Ac-Ala-Orn(dodecanoyl)-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Tyr-Ala-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Ala-Orn(dodecanoyl)-Ala-NH₂ 生物信息 纯度 ≥95% by HPLC 理化信息 溶解度 H₂O 肽序列 Ac-Ala-Orn(dodecanoyl)-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Tyr-Ala-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Ala-Orn(dodecanoyl)-Ala-NH₂ 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Irritant
储存 +2°C to +8°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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