merck millipore,默克密理愽
  • merck millipore,默克密理博,05-1563,Anti-PI3-kinase type 3 Antibody, clone 17D1.1

  • merck millipore,默克密理博,05-1563,Anti-PI3-kinase type 3 Antibody, clone 17D1.1

    产品名称：Anti-PI3-kinase type 3 Antibody, clone 17D1.1
    产品型号：05-1563
    Anti-PI3-kinase type 3 Antibody, clone 17D1.1 detects level of PI3-kinase type 3 & has been published & validated for use in WB & IC.

    merck millipore,默克密理博,05-1563,Anti-PI3-kinase type 3 Antibody, clone 17D1.1

  • 产品介绍
  • merck millipore,默克密理博,05-1563,Anti-PI3-kinase type 3 Antibody, clone 17D1.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MICC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 05-1563
    描述 Anti-PI3-kinase type 3 Antibody, clone 17D1.1
    Alternate Names
    • hVps34
    • Phosphatidylinositol 3-kinase catalytic subunit type 3
    • PI3-kinase type 3
    • PI3K type 3
    • PtdIns-3-kinase type 3
    • Phosphatidylinositol 3-kinase p100 subunit
    • Phosphoinositide-3-kinase class 3
    背景信息 PI3-kinase type 3 (also known as VPS34 or PIK3C3) is a member of the phosphatidylinositide 3-kinase family and plays a role in phosphoinositide lipid metabolism. PI3-kinase type 3 may be important in the pathogenesis of schizophrenia. PI3-kinase type 3 has also been found to regulate many different portions in the endosomal and autophagic pathways. A PI3-kinase type 3 deficiency has shown severe failing in cell proliferation and embryogenesis, missing the mesoderm development.
    产品信息
    格式 Purified
    控制
    • NIH3T3 cell lysate
    演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
    应用
    应用 Anti-PI3-kinase type 3 Antibody, clone 17D1.1 detects level of PI3-kinase type 3 & has been published & validated for use in WB & IC.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human PI3-kinase type 3.
    克隆 17D1.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgMκ
    品种反应性 RatHumanMouse
    Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_002638
    基因符号
    • VPS34
    • PIK3C3
    纯化方法 Affinity purified
    UniProt编号
    • Q8NEB9
    UniProt汇总 FUNCTION: Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis.

    CATALYTIC ACTIVITY: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.

    COFACTOR: Manganese.

    SUBUNIT STRUCTURE: Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4. Forms a complex with BECN1, PIK3R4 and either UVRAG and KIAA0226/Rubicon, or with ATG14. In this complex, presence of UVRAG and ATG14 are mutually exclusive.

    SUBCELLULAR LOCATION: Midbody.

    TISSUE SPECIFICITY: Ubiquitously expressed, with a highest expression in skeletal muscle.

    SEQUENCE SIMILARITIES: Belongs to the PI3/PI4-kinase family. Contains 1 PI3K/PI4K domain.
    产品使用声明
    质量保证 Evaluated by Western Blot in NIH3T3 cell lysate.

    Western Blot Analysis: 1 µg/mL of this antibody detected PI3-kinase type 3 on 10 µg of NIH3T3 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,05-1563,Anti-PI3-kinase type 3 Antibody, clone 17D1.1

上一件merck millipore产品：merck millipore,默克密理博,17-10242,ChIPAb+™ Trimethyl-Histone H3 (Lys9) - ChIP Validated Antibody and Primer Set
下一件merck millipore产品：merck millipore,默克密理博,05-1430,Anti-Neurofibromin Antibody, clone NFn27b


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