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merck millipore,默克密理博,343290,Fluoxetine, Hydrochloride - CAS 59333-67-4 - Calbiochem
产品名称：Fluoxetine, Hydrochloride - CAS 59333-67-4 - Calbiochem
产品型号：343290
A cell-permeable phenylpropylamine derived anti-depressant that acts as a selective serotonin re-uptake inhibitor (SSRI).
merck millipore,默克密理博,343290,Fluoxetine, Hydrochloride - CAS 59333-67-4 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₇H₁₈F₃NO • HCL 59333-67-4 描述 概述 A cell-permeable phenylpropylamine derived anti-depressant that acts as a selective serotonin re-uptake inhibitor (SSRI). Reported to modulate the proliferation of T-cells by increasing the Ca2+ influx and thereby influencing the activities of protein kinase A (PKA) and protein kinase C (PKC). Also shown to regulate the phosphorylation of DARPP-32 (dopamine-and cAMP-regulated phosphoprotein of Mr 32,000) and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors. Shown to trigger oxidative stress-induced apoptotic cell death. Also reported to initiate signaling pathways in neuronal cells leading to activation of ERK and NF-κB. 产品目录编号 343290 品牌系列 Calbiochem®
同义词 dl-N-Methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine, HCl, (±)-N-Methyl-3-phenyl-3-[(α,α,α-trifluoro-p-tolyl)oxy]propylamine, HCl, LY-110140, Prozac 参考 参考 Bartholoma, P., et al. 2002. Biochem. Pharmacol. 63, 1507.
Bian, J.T., et al. 2002. Eur. J. Pharmacol. 453, 159.
Zhang, A., et al. 2002. J. Med. Chem. 45, 1930.
Svenningsson, P., et al. 2002. Proc. Natl. Acad. Sci. USA 99, 3182.
Edgar, V.A., et al. 1999. Eur. J. Pharmacol. 372, 65.产品信息 CAS号 59333-67-4 具有ATP竞争性 N 形式 Solid Hill配方 C₁₇H₁₈F₃NO • HCL 化学配方 C₁₇H₁₈F₃NO • HCL Molar Mass 345.8 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 Selective serotonin re-uptake inhibitor 纯度 ≥98% by HPLC 理化信息 细胞可渗透 Y 溶解度 MeOH or H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful
储存 +2°C to +8°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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