merck millipore,默克密理愽
  • merck millipore,默克密理博,05-1527,Anti-eIF4A3 Antibody, clone 3F1

  • merck millipore,默克密理博,05-1527,Anti-eIF4A3 Antibody, clone 3F1

    产品名称：Anti-eIF4A3 Antibody, clone 3F1
    产品型号：05-1527
    Use Anti-eIF4A3 Antibody, clone 3F1 (mouse monoclonal antibody) validated in WB, IP, ICC to detect eIF4A3 also known as ATP-dependent RNA helicase DDX48, Eukaryotic translation initiation factor 4A is More>>

    merck millipore,默克密理博,05-1527,Anti-eIF4A3 Antibody, clone 3F1

  • 产品介绍
  • merck millipore,默克密理博,05-1527,Anti-eIF4A3 Antibody, clone 3F1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HICC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 05-1527
    描述 Anti-eIF4A3 Antibody, clone 3F1
    Alternate Names
    • hNMP 265
    • ATP-dependent RNA helicase DDX48
    • ATP-dependent RNA helicase eIF4A-3
    • DEAD (Asp-Glu-Ala-Asp) box polypeptide 48
    • DEAD box protein 48
    • Eukaryotic initiation factor 4A-like NUK-34
    • Eukaryotic translation initiation factor 4A isoform 3
    • Nuclear matrix protein 265
    • eukaryotic translation initiation factor 4A, isoform 3
    背景信息 Eukaryotic translation initiation factor 4A, isoform 3, also known as eIF4A3, is a member of the DEAD box protein family. DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). This family of proteins are putative RNA helicases and are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. eIF4A3 is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.
    产品信息
    格式 Purified
    控制
    • HeLa cell lysate
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
    应用
    应用 Use Anti-eIF4A3 Antibody, clone 3F1 (mouse monoclonal antibody) validated in WB, IP, ICC to detect eIF4A3 also known as ATP-dependent RNA helicase DDX48, Eukaryotic translation initiation factor 4A isoform 3.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    应用说明 Immunoprecipitation: Reported by independent laboratory using representative lot.
    Immunocytochemistry: Reported by independent laboratory using representative lot.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human eIF4A3.
    表位 Unknown
    克隆 3 F 1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This antibody recognizes eIF4A3.
    同种型 IgG1κ
    品种反应性 MouseHuman
    Species Reactivity Note Demonstrated to react with Human. Predicted to react with mouse based on sequence homology.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_055555.1
    Entrez基因汇总 This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. [provided by RefSeq].
    基因符号
    • hNMP265
    • DDX48
    • EIF4AIII
    • NMP265
    • NUK-34
    • eIF4AIII
    纯化方法 Protein G purfied
    UniProt编号
    • P38919
    UniProt汇总 FUCTION: Binds to spliced mRNAs and is involved in nonsense-mediated decay of mRNAs containing premature stop codons.

    SUBUNIT STRUCTURE: Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, EIF4A3, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8. Part of the exon junction complex (EJC), a multisubunit complex which assembles near mRNA exon-exon junctions and which contains proteins involved in mRNA splicing, export, localization and nonsense-mediated decay. May interact with NOM1.

    SUBCELLULAR LOCATION: Nucleus.

    TISSUE SPECIFICITY: Ubiquitously expressed.

    SEQUENCE SIMILARITIES: Belongs to the DEAD box helicase family. eIF4A subfamily.

    Contains 1 helicase ATP-binding domain.

    Contains 1 helicase C-terminal domain. ...
    产品使用声明
    质量保证 Evaluated by Western Blot in HeLa cell lysate.

    Western Blot Analysis: 1 µg/mL of this antibody detected eIF4A3 on 10 µg in HeLa cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,05-1527,Anti-eIF4A3 Antibody, clone 3F1

上一件merck millipore产品：merck millipore,默克密理博,MABS733,Anti-ITPR1, clone EPR4536, Rabbit Monoclonal Antibody
下一件merck millipore产品：merck millipore,默克密理博,MABE89,Anti-Brm Antibody, clone 1H7A10


相关产品

merck millipore,默克密理博,662086,UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem merck millipore,默克密理博,662086,UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem

merck millipore,默克密理博,14-663,CaM Kinase I Protein, active, 10 µg merck millipore,默克密理博,14-663,CaM Kinase I Protein, active, 10 µg

merck millipore,默克密理博,ABC129,Anti-WWP2 Antibody merck millipore,默克密理博,ABC129,Anti-WWP2 Antibody

merck millipore,默克密理博,AB1964,Anti-N-WASP Antibody, phospho-specific [Ser484/Ser485] merck millipore,默克密理博,AB1964,Anti-N-WASP Antibody, phospho-specific [Ser484/Ser485]

merck millipore,默克密理博,MABS733,Anti-ITPR1, clone EPR4536, Rabbit Monoclonal Antibody merck millipore,默克密理博,MABS733,Anti-ITPR1, clone EPR4536, Rabbit Monoclonal Antibody

merck millipore,默克密理博,MABE89,Anti-Brm Antibody, clone 1H7A10 merck millipore,默克密理博,MABE89,Anti-Brm Antibody, clone 1H7A10

merck millipore,默克密理博,573113,Sucrose, Molecular Biology Grade - CAS 57-50-1 - Calbiochem merck millipore,默克密理博,573113,Sucrose, Molecular Biology Grade - CAS 57-50-1 - Calbiochem

merck millipore,默克密理博,HTS066M,ChemiSCREEN™ Human Y2 Neuropeptide Receptor Membrane Preparation merck millipore,默克密理博,HTS066M,ChemiSCREEN™ Human Y2 Neuropeptide Receptor Membrane Preparation

merck millipore,默克密理博,MAIPNTR10,MultiScreen IP 0.45 µm，无色，非无菌 merck millipore,默克密理博,MAIPNTR10,MultiScreen IP 0.45 µm，无色，非无菌

merck millipore,默克密理博,14-785,PI3 Kinase (p110α/p85α) murine, 10 µg merck millipore,默克密理博,14-785,PI3 Kinase (p110α/p85α) murine, 10 µg


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部