- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,14-785,PI3 Kinase (p110α/p85α) murine, 10 µg
产品名称：PI3 Kinase (p110α/p85α) murine, 10 µg
产品型号：14-785
Complex of N-terminal 6His-tagged, recombinant, full-length mouse p110α & untagged, recombinant, full length mouse p85α. Coexpressed by baculovirus in Sf21 insect cells. For use in Kinase Assays.
merck millipore,默克密理博,14-785,PI3 Kinase (p110α/p85α) murine, 10 µg
- 产品介绍
描述 产品目录编号 14-785 品牌系列 Upstate
商名 - Upstate
描述 PI3 Kinase (p110α/p85α) murine, 10 µg 概述 Complex of N-terminal 6His-tagged, recombinant, full-length mouse p110αand untagged, recombinant, full length mouse p85α. Coexpressed by baculovirus in Sf21 insect cells. 应用 应用 Complex of N-terminal 6His-tagged, recombinant, full-length mouse p110α & untagged, recombinant, full length mouse p85α. Coexpressed by baculovirus in Sf21 insect cells. For use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Coexpressed by baculovirus in Sf21 insect cells. 品种 Mouse 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_006218.2
Entrez基因汇总 Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. 基因符号 - MGC142163
- PIK3CA
- PI3K
- MGC142161
- p110-alpha
蛋白靶 PI3Kα/p85α 纯化方法 Ni2+/NTA-agarose 靶子系列 PI3K/PI4K UniProt编号 - P42336
UniProt汇总 FUNCTION: SwissProt: P42336 # Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2.
SIZE: 1068 amino acids; 124284 Da
SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Binds to IRS1 in nuclear extracts. Interacts with RUFY3 (By similarity).
DISEASE: SwissProt: P42336 # Defects in PIK3CA are associated with colorectal cancer (CRC) [MIM:114500]. & Defects in PIK3CA are associated with breast cancer [MIM:114480]. & Defects in PIK3CA are associated with epithelial ovarian cancer (EOC) [MIM:604370].
SIMILARITY: SwissProt: P42336 ## Belongs to the PI3/PI4-kinase family. & Contains 1 C2 domain. & Contains 1 PI3K/PI4K domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap. 包装信息 数量 10 µg 包装 Also available in 250μg size --call for pricing and availability and reference catalog number 14-785M when ordering the 250μg size.
上一件merck millipore产品：merck millipore,默克密理博,MAIPNTR10,MultiScreen IP 0.45 µm，无色，非无菌
下一件merck millipore产品：merck millipore,默克密理博,MAB361,Anti-Tau Antibody, a.a. 210-241, clone Tau-5
相关产品
merck millipore,默克密理博,05-1527,Anti-eIF4A3 Antibody, clone 3F1
merck millipore,默克密理博,MABE89,Anti-Brm Antibody, clone 1H7A10
merck millipore,默克密理博,573113,Sucrose, Molecular Biology Grade - CAS 57-50-1 - Calbiochem
merck millipore,默克密理博,HTS066M,ChemiSCREEN™ Human Y2 Neuropeptide Receptor Membrane Preparation
merck millipore,默克密理博,MAIPNTR10,MultiScreen IP 0.45 µm，无色，非无菌
merck millipore,默克密理博,MAB361,Anti-Tau Antibody, a.a. 210-241, clone Tau-5
merck millipore,默克密理博,SF-1820,KAT6A; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,SF-410,KIT; Human, Cyanine 5, RNA Detection Probe,SmartFlare