• merck millipore,默克密理博,662086,UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem
  • merck millipore,默克密理博,662086,UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem

    产品名称:UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem
    产品型号:662086
    The UCH-L1 Inhibitor, also referenced under CAS 668467-91-2, controls the biological activity of UCH-L1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

    merck millipore,默克密理博,662086,UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,662086,UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₇H₁₁Cl₃N₂O₃668467-91-2
    描述
    概述 An isatin O-acyl oxime compound that acts as a potent, reversible, competitive, and active site-directed inhibitor of UCH-L1 (Ki = 0.40 µM; IC50 = 0.88 µM) with ~28-fold greater selectivity over UCH-L3 (Cat. No. 662090). Shown to increase proliferation of UCH-L1 expresssing tumor cell line SH-SY5Y at 5 µM. A useful tool for studying the roles of UCH-L1 in cancer, Parkinson’s disease, and other neurological disorders. Permeability may vary from cell type to cell type.
    产品目录编号 662086
    品牌系列 Calbiochem®
    同义词 LDN-57444, Ubiquitin C-Terminal Hydrolase L1 Inhibitor, Ubiquitin C-Terminal Esterase L1 Inhibitor, Ubiquitin Thiolesterase L1 Inhibitor
    参考
    参考 Liu, Y., et al. 2003. Chem. Biol. 10, 837.
    产品信息
    CAS号 668467-91-2
    具有ATP竞争性 Y
    形式 Orange solid
    Hill配方 C₁₇H₁₁Cl₃N₂O₃
    化学配方 C₁₇H₁₁Cl₃N₂O₃
    Molar Mass 397.6
    可逆 Y
    结构配方图像
    生物信息
    主靶 UCH-L1
    主靶IC50 0.88 µM
    主靶Ki 0.40 µM
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Carcinogenic / Teratogenic
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,662086,UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem

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