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描述 产品目录编号 14-527M 品牌系列 Upstate
商名 - Upstate
描述 Ros Protein, active, 250 µg 概述 N-terminal His6-tagged recombinant human Ros residues 1883-end 应用 应用 Active, N-terminal His6-tagged recombinant human Ros residues 1883-end, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 expressed by baculovirus in Sf21 insect cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_002944.2
Entrez基因汇总 This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. 基因符号 - OTTHUMP00000040389
- ROS1
- MCF3
- ROS
蛋白靶 Ros 纯化方法 Ni2+/NTA-agarose 靶子系列 TK UniProt编号 - P08922
UniProt汇总 FUNCTION: SwissProt: P08922 # This is probably a cell growth or differentiation factor receptor with a tyrosine-protein kinase activity.
SIZE: 2347 amino acids; 263915 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
DISEASE: SwissProt: P08922 # A chromosomal aberration involving ROS1 is found in glioblastoma multiform (GBM). An homozygous deletion in chromosome 6q21 results in expression of a GOPC-ROS1 chimeric protein which has a constitutive receptor tyrosine kinase activity.
SIMILARITY: SwissProt: P08922 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. & Contains 9 fibronectin type-III domains. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of KKKSPGEYVNIEFG 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-527) and in bulk (cat# 14-527-K).
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