merck millipore,默克密理博,04-1074,Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal

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merck millipore,默克密理博,04-1074,Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal
产品名称：Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal
产品型号：04-1074
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Anti-PECAM-1 [CD31] Antibody, clone EP3095, Rabbit d More>>

merck millipore,默克密理博,04-1074,Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal

产品介绍

merck millipore,默克密理博,04-1074,Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	FC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	04-1074
描述	Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal
Alternate Names	platelet/endothelial cell adhesion mo CD31 antigen PECAM-1, CD31/EndoCAM adhesion molecule
背景信息	CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1) is a type I integral membrane glycoprotein, and a member of the immunoglobulin superfamily of cell surface receptors. PECAM-1 is constitutively expressed on the surface of endothelial cells where it is concentrated at cell junctions. PECAM-1 is also expressed at low levels on all leukocytes and platelets. Homotypic interaction of CD31 is important in cell-cell interaction, cell-matrix interaction and signal transduction.

产品信息
格式	Unpurified
控制	THP-1 and Jurkat cell lysates
演示	Rabbit Monoclonal in buffer containing 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl containing 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Anti-PECAM-1 [CD31] Antibody, clone EP3095, Rabbit detects level of PECAM-1 [CD31] & has been published & validated for use in WB, IH(P), FC.
主要应用	Flow Cytometry Western Blotting
应用说明	Immunohistochemistry Analysis: 1:250 - 500 dilution from a previous lot detected PECAM1 in human uterus and tonsil tissue. Flow Cytometry: 1:70 dilution from a previous lot was used on FC.

生物信息
免疫原品种	Synthetic peptide corresponding to residues on human PECAM-1.
克隆	EP3095
宿主	Rabbit
特异性	This antibody recognizes PECAM1.
同种型	IgG
品种反应性	Human
Species Reactivity Note	Human
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_000433.3
基因符号	PECAM-1 CD31 CD31/EndoCAM EndoCAM GPIIA'
纯化方法	Unpurified
UniProt编号	P16284
UniProt汇总	FUNCTION: This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Long isoform predominates all tissues examined, isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung, isoform Delta14 was detected in all tissues examined with the strongest expression in heart. PTM: Phosphorylated on Ser and Tyr residues after cellular activation. SEQUENCE SIMILARITIES: Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

产品使用声明
质量保证	Evaluated by Western Blot on THP-1 and Jurkat cell lysates. Western Blot Analysis: 1:5,000 - 20,000 dilution of this antibody was used to detect PECAM1 in THP-1 and Jurkat cell lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerolcontaining solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20ºC from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerolcontaining solutions to become frozen during storage.