merck millipore,默克密理愽
  • merck millipore,默克密理博,RV2MAG-26K,MILLIPLEX MAP Rat Vascular Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay

  • merck millipore,默克密理博,RV2MAG-26K,MILLIPLEX MAP Rat Vascular Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay

    产品名称：MILLIPLEX MAP Rat Vascular Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay
    产品型号：RV2MAG-26K
    The analytes available for this multiplex kit are: Adiponectin, sE-Selectin, sICAM-1, von Willebrand Factor (vWF).

    merck millipore,默克密理博,RV2MAG-26K,MILLIPLEX MAP Rat Vascular Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay

  • 产品介绍
  • merck millipore,默克密理博,RV2MAG-26K,MILLIPLEX MAP Rat Vascular Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay

    重要规格表

    可用的分析物 品种反应性 主要应用 检测方法
    von Willebrand Factor (vWF), Adiponectin, sE-Selectin, sICAM-1RMplexLuminex xMAP
    描述
    产品目录编号 RV2MAG-26K
    商名
    • MILLIPLEX
    描述 MILLIPLEX MAP Rat Vascular Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay
    概述 The MILLIPLEX® MAP Rat Vascular Injury Magnetic Bead Panel 2 contains all the components necessary to measure the following four biomarkers in any combination using Luminex® xMAP® technology: Adiponectin, sE-Selectin, sICAM-1, von Willebrand Factor (vWF). The kit uses a 96-well format, contains a lyophilized standard cocktail, two quality controls and can measure up to 38 serum or plasma samples in duplicate.
    背景信息 Vascular injury is important to address during the preclinical safety study of drugs. A lack of well-defined mechanisms of drug-induced vascular injury (DIVI) in animals, and the absence of specific, qualified biomarkers have become significant barriers in the development of new therapeutic treatments. In the past, hemodynamics, such as heart rate and mean arterial blood pressure, were used to measure DIVI risks but these only targeted single biomarkers. Today, some of the known vascular injury mechanisms are related to vascular wall shear and/or circumferential “hoop” stress, drug/chemical toxicity, and immunological mediation. With these known biomechanics, primary targets (smooth muscle, endothelial and immune-mediated cells) yield a number of promising candidate biomarkers for DIVI study. We provide valuable research assays to investigate multiple biomarkers of vascular injury in rat serum and plasma samples using the Luminex xMAP® instrument platform.
    产品信息
    检测方法 Luminex xMAP
    配置 Design your multiplex kit by choosing analytes.
    精度（%）
    • Intra-Assay: < 10
    • Inter-assay: < 10
    板面类型 MAGNETIC Toxicity
    应用
    应用 The analytes available for this multiplex kit are: Adiponectin, sE-Selectin, sICAM-1, von Willebrand Factor (vWF).
    主要应用
    • Multiplexing
    应用说明 • This is an overnight assay.
    • This assay requires 25 µL of 1:80 diluted serum or plasma sample per well in kit Assay Buffer (please dilute per protocol instructions).
    生物信息
    特异性 There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
    品种反应性 Rat
    可用的分析物
    • von Willebrand Factor (vWF)
    • Adiponectin
    • sE-Selectin
    • sICAM-1
    化验面板 Everything you need in a single kit.
    交叉反应性 There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
    准确度
    • 67% - 92%
    理化信息
    灵敏度
    • See kit protocol for individual analytes sensitivities.
    稀释的线性 Contact technical support for this information.
    标准曲线范围
    • von Willebrand Factor (vWF): 0.7 – 500 ng/mL
    • Adiponectin: 0.3 – 250 ng/mL
    • sE-Selectin: 0.1 – 50 ng/mL
    • sICAM-1: 0.1 – 40 ng/mL
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Recommended storage for kit components is 2 - 8°C.
    包装信息
    数量 96-well plate

    merck millipore,默克密理博,RV2MAG-26K,MILLIPLEX MAP Rat Vascular Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay

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