merck millipore,默克密理博,MAB10142,Anti-Brachyury 2 Antibody, clone 4G7

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	M	Culture Supernatant	Monoclonal Antibody

描述
产品目录编号	MAB10142
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-Brachyury 2 Antibody, clone 4G7
背景信息	The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.

产品信息
格式	Culture Supernatant
演示	Liquid containing 0.1% sodium azide.

应用
应用	Anti-Brachyury 2 Antibody, clone 4G7 is an antibody against Brachyury 2 for use in WB.
主要应用	Western Blotting

生物信息
免疫原品种	Recombinant human Brachyury 2
克隆	4G7
宿主	Mouse
同种型	IgG2a
品种反应性	Human
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_003181.2
Entrez基因汇总	The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.
基因符号	TFT T MGC104817 TF
UniProt编号	O15178
UniProt汇总	FUNCTION: SwissProt: O15178 # Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. SIZE: 435 amino acids; 47443 Da SUBUNIT: Monomer (By similarity). SUBCELLULAR LOCATION: Nucleus. DISEASE: SwissProt: O15178 # Genetic variations in T are associated with susceptibility to neural tube defects (NTD) [MIM:182940]. NTD are common congenital malformations. Spina bifida, which results from malformations in the caudal region of the neural tube, is compatible with life but associated with significant morbidity, including lower limb paralysis. SIMILARITY: SwissProt: O15178 ## Contains 1 T-box DNA-binding domain.

产品使用声明
质量保证	Routinely evaluated by immunoblot.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	1 year at 4°C from date of shipment

包装信息
数量	100 µL

merck millipore,默克密理博,MAB10142,Anti-Brachyury 2 Antibody, clone 4G7

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