merck millipore,默克密理博,MGAMMAG-300K,MILLIPLEX MAP Mouse Immunoglobulin Isotyping Magnetic Bead Panel

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Merck Millipore 默克密理愽

merck millipore,默克密理博,MGAMMAG-300K,MILLIPLEX MAP Mouse Immunoglobulin Isotyping Magnetic Bead Panel - Isotyping Multiplex Assay

Replacement Information
Replacement Information	This product replaces Mouse Immunoglobulin Isotyping Kit, MGAM-300 in December of 2011 or while supplies last.

可用的分析物	品种反应性	主要应用	检测方法
IgM, IgG1, IgG2a, IgG2b, IgG3, IgA	M	Mplex	Luminex xMAP

描述
产品目录编号	MGAMMAG-300K
Replaces	MGAM-300
商名	MILLIPLEX
描述	MILLIPLEX MAP Mouse Immunoglobulin Isotyping Magnetic Bead Panel - Isotyping Multiplex Assay
概述	MILLIPLEX MAP Mouse Isotyping Magnetic Bead Panel, measuring mouse IgG subclasses (1, 2a, 2b, 3), IgM, and IgA, has been designed to enable you to measure both classes and subclasses accurately – all in one well. In addition this panel allows you to choose only those immunoglobulins you need for your experiments.
背景信息	Produced by plasma cells and lymphocytes, immunoglobulins (antibodies) are critically involved in immune response, attaching to antigens and playing a role in their destruction. Immunoglobulins (Ig) can be classified by isotype, classes that differ in function and antigen response due to structure variability. Six major isotypes have been identified in placental mammals: IgM, IgG1, IgG2a, IgG2b, IgG3 and IgA – all found in normal individuals. Immunoglobulin-deficiency disorders, such as autoimmune disease, some GI conditions and malignancies, are characterized by specific isotype deficiencies or varying concentrations of one or more isotypes. Disease states can range from the absence of one isotype class or subclass to a total deficiency of immunoglobulin classes.

产品信息
检测方法	Luminex xMAP
配置	Design your multiplex kit by choosing analytes.
精度（%）	Inter-Assay 14 - 17% Intra-Assay 5 - 10%
板面类型	MAGNETIC Immune Response

应用
应用	The analytes available for this multiplex kit are: IgG1, IgG2a, IgG2b, IgG3, IgA, IgM.
主要应用	Multiplexing
应用说明	• This kit may be used for the analysis of IgG1, IgG2a, IgG2b, IgG3, IgA and IgM in mouse serum or tissue/cell lysate and culture supernatant samples. • There are 2 one-hour room-temperature incubations. • This assay requires 50 µl of 1:50,000 diluted plasma or serum, or 50 μL cell culture supernatant diluted to approximately 1μg/mL Ig per well.

生物信息
特异性	Cross-reactivity between these antibodies and those against other immunoglobulins is non-detectable or negligible.
品种反应性	Mouse
Species Reactivity Note	Mouse
可用的分析物	IgM IgG1 IgG2a IgG2b IgG3 IgA
准确度	IgM 100% IgG1 96% IgG2a 76% IgG2b 98% IgG3 85% IgA 98%

理化信息
灵敏度	IgM 1.73 ng/mL IgG1 0.7 ng/mL IgG2a 0.67 ng/mL IgG2b 0.18 ng/mL IgG3 0.32 ng/mL IgA 1.1 ng/mL
标准曲线范围	IgM: 2 – 1,500 ng/mL IgG1: 2 – 1,500 ng/mL IgG2a: 3 – 2,000 ng/mL IgG2b: 1 – 900 ng/mL IgG3: 2 – 1,500 ng/mL IgA: 5 – 3,000 ng/mL

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Recommended storage for kit components is 2 - 8°C.

包装信息
数量	96-well plate
包装	96 Well Plate

merck millipore,默克密理博,MGAMMAG-300K,MILLIPLEX MAP Mouse Immunoglobulin Isotyping Magnetic Bead Panel - Isotyping Multiplex Assay

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