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merck millipore,默克密理博,MCH200108,Muse™PI3K/MAPK Dual Pathway Activation Kit
产品名称:Muse™PI3K/MAPK Dual Pathway Activation Kit
产品型号:MCH200108
The Muse PI3K/MAPK Dual Pathway Activation Kit is designed to enable researchers a quick and easy way to cross examine both the PI3K and MAPK signaling pathways simultaneously using the Muse Cell An More>>
merck millipore,默克密理博,MCH200108,Muse™PI3K/MAPK Dual Pathway Activation Kit
- 产品介绍
描述 产品目录编号 MCH200108 商名 - Muse
描述 Muse™PI3K/MAPK Dual Pathway
Activation Kit概述 EMD Millipore’s Muse™ PI3K/MAPK Dual Pathway Activation Kit is designed to enable researchers a quick and easy way to cross examine both the PI3K and MAPK signaling pathways simultaneously using the Muse Cell Analyzer. Recent evidence suggests that there is cross-talk between the PI3K and the MAPK signaling pathways. Antibodies against phosphorylated Akt (pAkt) and phosphorylated ERK (pERK) can be used to examine PI3K/MAPK interactions. Data generated using the Muse™ Cell Analyzer along with the corresponding Muse™ software module provides statistical values measuring:
• Percentage of negative cells (e.g. no PI3K or MAPK pathway activation)
• Percentage of ERK1/2 activated cells (MAPK pathway activation)
• Percentage of Akt activated cells (PI3K pathway activation)
• Percentage of dual pathway activation (MAPK and PI3K pathway activation)
The Muse™ PI3K/MAPK Dual Pathway Activation Kit includes two directly conjugated antibodies, a phospho-specific Akt (Ser473)-Alexa Fluor®555 and a phospho-specific ERK1/2 (Thr202/Tyr204, Thr185/Tyr187)-PECy5 conjugated antibody to assess the activation of both the PI3K and MAPK signaling pathways simultaneously in testing samples. Together, two color analysis of Akt and ERK1/2 activation in multiplex provides a reliable detection method for assessing the interactions and possible cross-talk activities for these two key signaling pathways. Both antibodies provided in the kit are carefully titrated and optimized together to ensure maximal performance when run in multiplex, alleviating the need for any additional optimization. This kit contains optimized fixation, permeabilization, and assay buffers to provide researchers with a complete solution for PI3K and MAPK cell signaling analysis.
The Muse™ PI3K/MAPK Dual Pathway Activation Kit is optimized on the Muse™ Cell Analyzer. The Muse™ System makes sophisticated fluorescent-based analysis fast, easy, convenient, and affordable. Sample preparation is minimal, and after loading samples onto the Muse™ Cell Analyzer, the intuitive software provides detailed or summary analysis of your cell sample in a few short steps. Sufficient reagent is provided for the preparation and analysis of 50 tests.
For Research Use Only; not for use in diagnostic procedures.应用 应用 The Muse® PI3K/MAPK Dual Pathway Activation Kit is designed to enable researchers a quick and easy way to cross examine both the PI3K and MAPK signaling pathways simultaneously using the Muse® Cell Analyzer. 产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 100 Tests
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