merck millipore,默克密理愽
  • merck millipore,默克密理博,MABT376,Anti-Ero1 Antibody, clone 2G4/12

  • merck millipore,默克密理博,MABT376,Anti-Ero1 Antibody, clone 2G4/12

    产品名称：Anti-Ero1 Antibody, clone 2G4/12
    产品型号：MABT376
    Anti-Ero1 Antibody, clone 2G4/12 is a highly specific mouse monoclonal antibody, that targets ERO1-like protein alpha & has been tested in western blotting, IP & Immunofluorescence.

    merck millipore,默克密理博,MABT376,Anti-Ero1 Antibody, clone 2G4/12

  • 产品介绍
  • merck millipore,默克密理博,MABT376,Anti-Ero1 Antibody, clone 2G4/12

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABT376
    描述 Anti-Ero1 Antibody, clone 2G4/12
    Alternate Names
    • Oxidoreductin-1-L-alpha
    • ERO1-like protein alpha, ERO1-L
    • ERO1-L-alpha, Endoplasmic oxidoreductin-1-like protein
    背景信息 ERO1-like protein alpha (ERO1) is also called endoplasmic oxidoreductin-1-like protein and Oxidoreductin-1-L-alpha. ERO1 is an essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. ERO1 is stimulated by hypoxia, indicating that it is regulated by the HIF-pathway. ERO1 may be responsible for much of the reactive oxygen species (ROS) in the cell, and therefore is a source of oxidative stress. EROS1 is required for the folding of immunoglobulin proteins, responsible for the release of the unfolded cholera toxin, and plays an important role in ER stress-induced, CHOP-dependent apoptosis. ERO1 is widely expressed at low levels, with high levels in upper digestive tract.
    产品信息
    格式 Purified
    控制
    • HEK293 cell lysate
    演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Ero1 Antibody, clone 2G4/12 is a highly specific mouse monoclonal antibody, that targets ERO1-like protein alpha & has been tested in western blotting, IP & Immunofluorescence.
    主要应用
    • Western Blotting
    应用说明 Western Blotting Analysis: 1 µg/mL from a representative lot detected Ero1 from 10 µg of the following cell lysates--A431, HEK293, HeLa, HepG2, human placenta tissue, HUVEC, jurkat, L6, NIH/3T3, PC12, PC3, and RAW264.7.

    Immunoprecipitation Analysis: A representative lot immunoprecipitated Ero1 in Ero1 transfected HeLa cell lysate (Prof. R. Sitia, San Rafaele Scientific Institute, Milano, Italy).

    Immunofluorescence Analysis: A representative lot detected Ero1 in HeLa cell lysate (Prof. R. Sitia, San Rafaele Scientific Institute, Milano, Italy).
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to Human Ero1.
    克隆 2G4/12
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2aκ
    品种反应性 RatHumanMouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_055399
    基因符号
    • ERO1L
    纯化方法 Protein G purified
    UniProt编号
    • Q96HE7
    产品使用声明
    质量保证 Evaluated by Western Blotting in HEK293 cell lysate.

    Western Blotting Analysis: 1 µg/mL of this antibody detected Ero1 in 10 µg of HEK293 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABT376,Anti-Ero1 Antibody, clone 2G4/12

上一件merck millipore产品：merck millipore,默克密理博,MAB10758,Anti-mouse Immunoglobulin kappa light chain Antibody, clone 187.1, Rat
下一件merck millipore产品：merck millipore,默克密理博,480708,α2-3,6-Neuraminidase, Clostridium perfringens, Recombinant, E. coli


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