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品种反应性 主要应用 宿主 格式 抗体类型 H WB, ELISA Gt Purified Polyclonal Antibody 描述 产品目录编号 AB3422 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Surfactant Protein A Antibody Alternate Names - SP-A
产品信息 格式 Purified 演示 Purified immunoglobulin. Liquid in PBS. Contains no preservative. 应用 应用 Detect Surfactant Protein A using this Anti-Surfactant Protein A Antibody validated for use in ELISA & WB. 主要应用 - Western Blotting
- ELISA
应用说明 Immunoblot: 1:1,000-1:5,000
ELISA: 1:500-1:1,000 Optimal dilutions must be determined by the end user.生物信息 免疫原品种 Human SP-A from human alveolar proteinosis lavage fluid. 宿主 Goat 特异性 Reacts strongly with human SP-A. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001093770.1
基因符号 - SP-A
- SFTPA1
- SFTP1
- COLEC4
- PSPA
- SFTPA
- PSP-A
- PSAP
- SP-A1
UniProt编号 - Q8IWL2
UniProt汇总 FUNCTION: SwissProt: Q8IWL2 # In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
SIZE: 248 amino acids; 26242 Da
SUBUNIT: Oligomeric complex of 6 set of homotrimers.
SUBCELLULAR LOCATION: Secreted, extracellular space.
DISEASE: SwissProt: Q8IWL2 # Genetic variations in SFTPA1 are associated with respiratory distress syndrome in premature infants (RDS) [MIM:267450]; also known as RDS in prematurity. RDS in the newborn is the main cause of mortality and morbidity in premature infants. RDS is characterized by deficient gas exchange that is caused by diffuse atelectasis and high-permeability lung edema that results in fibrin-rich alveolar deposits called 'hyaline membranes'. The risk of bronchopulmonary dysplasia increases with the severity of RDS.
SIMILARITY: SwissProt: Q8IWL2 ## Contains 1 C-type lectin domain. & Contains 1 collagen-like domain.
MISCELLANEOUS: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to twelve months. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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