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merck millipore,默克密理博,PK1013,PhosphoDetect™ Anti-c-Abl (pTyr²⁴⁵) Rabbit pAb
产品名称：PhosphoDetect™ Anti-c-Abl (pTyr²⁴⁵) Rabbit pAb
产品型号：PK1013
This PhosphoDetect™ Anti-c-Abl (pTyr²⁴⁵) Rabbit pAb is validated for use in Immunoblotting for the detection of c-Abl (pTyr²⁴⁵).
merck millipore,默克密理博,PK1013,PhosphoDetect™ Anti-c-Abl (pTyr²⁴⁵) Rabbit pAb
- 产品介绍
重要规格表
宿主 Rb 描述 概述 Recognizes the ~135 kDa c-Abl protein phosphorylated at Tyr245 in HEK293 cells over-expressing constitutively active c-Abl. Also recognizes the ~210 kDa BCR-Abl protein phosphorylated at Tyr245 in K562 cells. - Antibody Target Gene Symbol: ABL1
- Target Synonym: ABL, AI325092, bcr/abl, C-ABL, C-ABL 1B, CABL1, E430008G22Rik, JTK7, MGC117749, p145Abl, p150, v-abl
- Entrez Gene Name: c-abl oncogene 1, receptor tyrosine kinase
- Hu Entrez ID: 25 (Related Antibodies: OP20 PK1006 OP19)
- Mu Entrez ID: 11350
- Rat Entrez ID: 311860
产品目录编号 PK1013 品牌系列 Calbiochem®
同义词 Anti-p150, Phospho-Specific (Tyr²⁴⁵), Anti-Abl1, Phospho-Specific (Tyr²⁴⁵), Anti-c-Abl, Phospho-Specific (Tyr²⁴⁵) 应用数据 
Panel A: Detection of human c-Abl, phosphorylated on Tyr245, by immunoblotting. Samples: Whole cell lysate from HEK293 cells over-expressing wild-type c-Abl (lane 1) or constitutively active c-Abl (lane 2). Primary antibodies: PhosphoDetect™ Anti-c-Abl (pTyr245) Rabbit pAb (top panel) (Cat. No. PK1013) (1:1000) and Anti-c-Abl (total) (bottom panel). Detection: chemiluminescence. Panel B: Detection of human BCR-Abl, phosphorylated on Tyr245, by immunoblotting. Sample: Whole cell lysate from K562 cells left untreated (-) or treated with calf intestinal alkaline phosphatase (+). Primary antibody: PhosphoDetect™ Anti-c-Abl (pTyr245) Rabbit pAb (Cat. No. PK1013) (1:1000). Detection: chemiluminescence.参考 参考 Pluk, H., et al. 2002. Cell 108, 247.
Brasher, B.B. and Van Etten, R.A. 2000. J. Biol. Chem. 275, 35631.
Danial, N.N. and Rothman, P. 2000. Oncogene 19, 2523.
Shaul, Y. 2000. Cell Death Differ. 7, 10.
Wang, J.Y. 2000. Oncogene 19, 5643.
Van Etten, R.A. 1999. Trends Cell. Biol. 9, 179.产品信息 形式 Liquid 配方 In 150 mM NaCl, 10 mM sodium HEPES, 100 µg/ml BSA, 50% glycerol, pH 7.5. 正控制 HEK293 cells over-expressing constitutively active c-Abl and K562 cells (BCR-Abl) 防腐剂 None 应用 主要应用 Immunoblotting (Western Blotting)
生物信息 免疫原 a synthetic phosphopeptide corresponding to amino acids surrounding the Tyr²⁴⁵ phosphorylation site of human c-Abl, coupled to KLH 免疫原品种 Human 宿主 Rabbit 同种型 IgG 品种 human, mouse 储存和货运信息 货运代码 Blue Ice Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Do no aliquot.
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