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merck millipore,默克密理博,MABT104,Anti-Myotubularin Antibody, clone 9G3.2
产品名称：Anti-Myotubularin Antibody, clone 9G3.2
产品型号：MABT104
Detect Myotubularin using this Anti-Myotubularin Antibody, clone 9G3.2 validated for use in Western Blotting.
merck millipore,默克密理博,MABT104,Anti-Myotubularin Antibody, clone 9G3.2
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, M WB M Purified Monoclonal Antibody 描述 产品目录编号 MABT104 描述 Anti-Myotubularin Antibody, clone 9G3.2 Alternate Names - Myotubularin
背景信息 Myotubularin is a cytoplasmic phosphatase which belongs to the protein-tyrosine phosphatase family. It contains a GRAM domain and a myotubularin phosphatase domain. Myotubularin targets phosphoinositide substrates, including phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). It may also dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Myotubularin indirectly regulates many cellular processes that are facilitated by phosphoinositides, and plays an important role in the formation and morphology of membrane-bound intracellular structures such as vacuoles and mitochondria. It also regulates the transport of EGFR from late endosomes to lysosomes, resulting in the degradation of EGFR. Defects in myotubularin result in X-linked myotubular myopathy, a congenital muscle-wasting condition that affects the limb girdle, trunk, and neck muscles. It has also been implicated in other neuromuscular diseases, such as Charcot-Marie-Tooth disease type 4B. 产品信息 格式 Purified 控制 - Rat liver tissue lysate
演示 Purified mouse monoclonal IgMκ supernatant in buffer containing PBS with 0.05% sodium azide. 应用 应用 Detect Myotubularin using this Anti-Myotubularin Antibody, clone 9G3.2 validated for use in Western Blotting. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: 0.2 µg/mL of this antibody detected Myotubularin in mouse liver tissue lysate. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human Myotubularin. 克隆 9G3.2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgMκ 品种反应性 RatMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_000243
基因符号 - CG2
- MTM1
纯化方法 Purified by ion-exchange chromatography. UniProt编号 - Q13496
产品使用声明 质量保证 Evaluated by Western Blot in rat liver tissue lysate.
Western Blot Analysis: 0.2 µg/mL of this antibody detected Myotubularin in rat liver tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,MABN328,Anti-peptidyl-citrulline, clone F95 Antibody
下一件merck millipore产品：merck millipore,默克密理博,376650,D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem
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