merck millipore,默克密理愽
  • merck millipore,默克密理博,05-1109,Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01

  • merck millipore,默克密理博,05-1109,Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01

    产品名称：Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01
    产品型号：05-1109
    This Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01 is validated for use in IH(P) for the detection of Pro-Insulin C-Peptide.

    merck millipore,默克密理博,05-1109,Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01

  • 产品介绍
  • merck millipore,默克密理博,05-1109,Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIH(P)MPurifiedMonoclonal Antibody
    描述
    产品目录编号 05-1109
    Replaces CBL94
    描述 Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01
    Alternate Names
    • insulin receptor
    • CD220 antigen
    背景信息 Pro-Insulin consists of the three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the Insulin molecule). From every molecule of Pro-Insulin, one molecule of Insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to Insulin.
    产品信息
    格式 Purified
    控制
    • Human normal pancreas tissue
    演示 Mouse monoclonal IgG1 in phosphate buffered saline, pH7.4, and 15 mM sodium azide.
    应用
    应用 This Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01 is validated for use in IH(P) for the detection of Pro-Insulin C-Peptide.
    主要应用
    • Immunohistochemistry (Paraffin)
    生物信息
    免疫原品种 Synthetic C-peptide of human pro-insulin conjugated to bovine serum albumin.
    克隆 C-PEP-01
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 The antibody C-PEP-01 reacts specifically with C-peptide, a part of the Pro-insulin molecule.
    同种型 IgG1
    品种反应性 Human
    Species Reactivity Note Reacts with human. No cross-reactivity with Insulin or other peptide hormones or proteins was observed.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • P01308
    基因符号
    • proinsulin
    • ILPR
    • IRDN
    • OTTHUMP00000011161
    • OTTHUMP00000011162
    • OTTHUMP00000196038
    • insulin
    纯化方法 Sequential precipitation with caprylic acid and ammonium sulfate.
    UniProt编号
    • P01308
    UniProt汇总 FUNCTION: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    SUBUNIT STRUCTURE: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
    SUBCELLULAR LOCATION: Secreted.
    INVOLVEMENT IN DISEASE: Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
    PHARMACEUTICAL USE: Available under the names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk). Used in the treatment of diabetes. Humalog is an insulin analog with 52-Lys-Pro-53 instead of 52-Pro-Lys-53.
    SEQUENCE SIMILARITIES: Belongs to the insulin family.
    SEQUENCE CAUTION: The sequence AAA59179.1 differs from that shown. Reason: Erroneous gene model prediction.
    产品使用声明
    质量保证 Evaluated by Immunohistochemistry in normal human pancreas.
    Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected insulin in human normal pancreas tissue.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at 2-8°C and use within 1 year from date of receipt.
    包装信息
    数量 1 mg

    merck millipore,默克密理博,05-1109,Anti-Pro-Insulin C-Peptide Antibody, clone C-PEP-01

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