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  • merck millipore,默克密理博,FCABS377F,Milli-Mark™ Anti-Histone H2B-FITC Antibody

  • merck millipore,默克密理博,FCABS377F,Milli-Mark™ Anti-Histone H2B-FITC Antibody

    产品名称：Milli-Mark™ Anti-Histone H2B-FITC Antibody
    产品型号：FCABS377F
    Milli-Mark Anti-Histone H2B-FITC Antibody is an antibody against Histone H2B for use in FC.

    merck millipore,默克密理博,FCABS377F,Milli-Mark™ Anti-Histone H2B-FITC Antibody

  • 产品介绍
  • merck millipore,默克密理博,FCABS377F,Milli-Mark™ Anti-Histone H2B-FITC Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HFCRbFITCPolyclonal Antibody
    描述
    产品目录编号 FCABS377F
    商名
    • Milli-Mark
    描述 Milli-Mark™ Anti-Histone H2B-FITC Antibody
    Alternate Names
    • histone cluster 2, H2be
    • H2B
    • Histone H2B
    • H2B histone family, member Q
    • histone 2, H2be
    背景信息 Histone H2B is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome. Histones are modified post-translationally by the actions of enzymes in both the nucleus and cytoplasm. These modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). The modifications occur predominantly on the N-terminal and C-terminal tails that extend beyond the nucleosome core particle.
    产品信息
    格式 FITC
    控制
    • HeLa cells
    演示 Purified rabbit polyclonal IgG conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA
    应用
    应用 Milli-Mark Anti-Histone H2B-FITC Antibody is an antibody against Histone H2B for use in FC.
    主要应用
    • Flow Cytometry
    生物信息
    免疫原品种 Synthetic peptide corresponding to amino acids 118-126 of human Histone H2B, with an N-terminal CG added for conjugation purposes.
    宿主 Rabbit
    特异性 Antibody recognizes Histone H2B.
    同种型 IgG
    品种反应性 Human
    Species Reactivity Note Tested and passed on Human. Broad species cross-reactivity expected based on sequence homology. Unconjugated antibody Cat. No. 07-371 is known to react with Chicken, Xenopus, and Yeast (S. cerevisiae)
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_778225
    基因符号
    • H2B.q
    • GL105
    • H2B
    • H2B-GL105
    • H2B.1
    纯化方法 Protein A Purified
    UniProt编号
    • Q8N257
    UniProt汇总 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    产品使用声明
    质量保证 Evaluated by flow cytometry using HeLa cells.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
    包装信息
    数量 100 tests

    merck millipore,默克密理博,FCABS377F,Milli-Mark™ Anti-Histone H2B-FITC Antibody

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