• merck millipore,默克密理博,376650,D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem
  • merck millipore,默克密理博,376650,D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem

    产品名称:D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem
    产品型号:376650
    Biologically active, cell-permeable, non-physiological ceramide analog.

    merck millipore,默克密理博,376650,D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,376650,D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₄H₄₇NO₃124753-97-5
    描述
    概述 Biologically active, cell-permeable, non-physiological ceramide analog. Induces a dramatic arrest in the G0/G1 phase of the cell cycle. Activates MAP kinase. Activates protein phosphatase 2A (PP2A) at 10 nM. Inhibits diacylglycerol accumulation and phospholipase D (PLD) activation in fibroblasts. Induces apoptosis in MOLT-4 leukemia cells.
    产品目录编号 376650
    品牌系列 Calbiochem®
    同义词 C₆ Ceramide
    参考
    参考 Jayadev, S., et al. 1995. J. Biol. Chem. 270, 2047.
    Venable, M.E., et al. 1994. J. Biol. Chem. 269, 26040.
    Dobrowsky, R.T., et al. 1993. J. Biol. Chem. 268, 15523.
    Raines, M.A., et al. 1993. J. Biol. Chem. 268, 14572.
    Dobrowsky, R.T., and Hannun, Y.A. 1992. J. Biol. Chem. 267, 5048.
    产品信息
    CAS号 124753-97-5
    具有ATP竞争性 N
    形式 White waxy solid
    Hill配方 C₂₄H₄₇NO₃
    化学配方 C₂₄H₄₇NO₃
    Molar Mass 397.6
    可逆 N
    结构配方图像
    生物信息
    主靶 MAP kinase, protein phosphatase 2A (PP2A)
    主靶IC50 Effective concentration: 10 nM in activating protein phosphatase 2A (PP2A)
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    安全信息
    R相 R: 36/37/38

    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

    merck millipore,默克密理博,376650,D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,376650,D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,FCABS377F,Milli-Mark™ Anti-Histone H2B-FITC Antibody



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