merck millipore,默克密理博,MABS746,Anti-COPS5, clone EPR1350, Rabbit Monoclonal Antibody

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merck millipore,默克密理博,MABS746,Anti-COPS5, clone EPR1350, Rabbit Monoclonal Antibody
产品名称：Anti-COPS5, clone EPR1350, Rabbit Monoclonal Antibody
产品型号：MABS746
This Anti-COPS5, clone EPR1350, Rabbit Monoclonal Antibody is validated for use in Western Blotting for the detection of COPS5.

merck millipore,默克密理博,MABS746,Anti-COPS5, clone EPR1350, Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABS746,Anti-COPS5, clone EPR1350, Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABS746
描述	Anti-COPS5, clone EPR1350, Rabbit Monoclonal Antibody
Alternate Names	Jun activation domain-binding protein 1 COP9 signalosome complex subunit 5 SGN5 Signalosome subunit 5
背景信息	COP9 signalosome complex subunit 5 (SGN5 or Signalosome subunit 5), also kown as Jun activation domain-binding protein 1, and encoded by the gene names COPS5 or CSN5 or JAB1, is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. COPS5 is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	This Anti-COPS5, clone EPR1350, Rabbit Monoclonal Antibody is validated for use in Western Blotting for the detection of COPS5.
主要应用	Western Blotting
应用说明	Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to human COPS5.
克隆	EPR1350
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	RatHumanMouse
Species Reactivity Note	Human, Mouse, Rat
抗体类型	Monoclonal Antibody
基因符号	JAB1 COPS5 CSN5
纯化方法	Unpurified
UniProt编号	Q92905

产品使用声明
质量保证	Evaluated by Western Blotting in NIH/3T3, U87-MG, MCF7, and PC12 cell lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected COPS5 in NIH/3T3, U87-MG, MCF7, and PC12 cell lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.