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merck millipore,默克密理博,09-078,Anti-EHMT1/GLP1 Antibody
产品名称：Anti-EHMT1/GLP1 Antibody
产品型号：09-078
Use Anti-EHMT1/GLP1 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect EHMT1/GLP1 also known as H3-K9-HMTase 5, Histone H3-K9 methyltransferase 5.
merck millipore,默克密理博,09-078,Anti-EHMT1/GLP1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 09-078 品牌系列 Upstate
商名 - Upstate
描述 Anti-EHMT1/GLP1 Antibody Alternate Names - G9a like protein <br />H3-K9-HMTase <br />Histone H3-K9 methyltransferase <br />Histone-lysine N-methyltransferase, H3 lysine-9 specific <br />EC 2.1.1.43 <br />euchromatic histone methyltransferase 1<br />euchromatic histone-lysine N-methyltransferase 1 <br />Eu-HMTase1 <br />FLJ12879 1<br />FP13812 <br />GLP1 <br />KIAA1876 <br />KMT1D <br />bA188C12.1
- G9a like protein <br />H3-K9-HMTase <br />Histone H3-K9 methyltransferase <br />Histone-lysine N-methyltransferase
背景信息 G9a-Like Protein 1 (GLP1), also known as Euchromatic histone lysine N-methyl-transferase 1 (EMHT1), is a histone methyltransferase that methylates Lys9 of histone H3. H3Lys9 methylation is a marker for epigenetic transcriptional repression. EMHT1/GLP1 is targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it contributes to silencing of Myc- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. EMHT1/GLP1 is phosphorylated upon DNA damage, probably by ATM or ATR. Defects in EHMT1 result in severe mental retardation, hypotonia, and epileptic seizures. 产品信息 格式 Affinity Purified 演示 Immunoaffinity purified rabbit IgG in PBS containing 0.1% sodium azide, 30% glycerol 应用 应用 Use Anti-EHMT1/GLP1 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect EHMT1/GLP1 also known as H3-K9-HMTase 5, Histone H3-K9 methyltransferase 5. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH conjugated synthetic peptide (KHTQDSARVNPQDGTNTLTR(C) corresponding to a.a. 40-59 of human EMHT1/GLP1. 表位 a.a. 40-59 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes EMHT1/GLP1 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - 79813
- NM_012117.1
基因符号 - KIAA1876
- EHMT1
- EUHMTASE1
- KMT1D
纯化方法 Immunoaffinity purified UniProt编号 - Q9H9B1
UniProt汇总 Histone methyltransferase. Methylates 'Lys-9' of histone H3 (in vitro). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1proteins to methylated histones. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle.
Enzyme Number (IUBMB): EC 2.1.1.43产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance包装信息 数量 100 µg
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