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品种反应性 主要应用 宿主 格式 抗体类型 H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABS182 描述 Anti-HOP Antibody, clone 17E8.1 Alternate Names - Transformation-sensitive protein IEF SSP 3521
- Stress-induced-phosphoprotein 1
- STI1
- Hsc70/Hsp90-organizing protein
- Hop
- Renal carcinoma antigen NY-REN-11
背景信息 Hsc70/Hsp90-organizing protein (HOP), also known as Stress-induced-phosphoprotein 1 (STI1 or STIP1) and Renal carcinoma antigen NY-REN-11, mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB) and also interacts with PACRG. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. HOP also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones. HOP is critically involved in endothelial cell migration and angiogenesis. 产品信息 格式 Purified 控制 - HeLa cell lysate
演示 Purified mouse monoclonal IgG3κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This HOP antibody is validated for use in WB for the detection of the HOP protein. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human HOP. 克隆 17E8.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG3κ 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_006810
基因符号 - STIP1
纯化方法 Protein G purified UniProt编号 - P31948
产品使用声明 质量保证 Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 0.2 µg/mL of this antibody detected HOP in 200 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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