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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS379 Replaces MABF196 描述 Anti-GARS Antibody Alternate Names - GlyRS
- Glycine--tRNA ligase
- Diadenosine tetraphosphate synthetase
- AP-4-A synthetase
- Glycyl-tRNA synthetase
背景信息 Glycine--tRNA ligase (GARS) is a member of the class-II aminoacyl-tRNA synthetase family which produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. GARS is widely expressed with levels found in the brain and spinal cord. Mutations in GARS have been associated with Charcot-Marie-Tooth disease type 2D and distal hereditary motor neuronopathy type 5A. 产品信息 格式 Affinity Purified 控制 - Human brain tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide with 50% glycerol. 应用 应用 Anti-GARS Antibody is a rabbit polyclonal antibody, validated for use in western blotting, IHC & Immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected GARS in skin cancer tissue.
Immunofluorescence Analysis: A 1:25 dilution from a representative lot detected GARS in HepG2 cells.生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human GARS. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - GARS
纯化方法 Antigen Affinity purified UniProt编号 - P41250
产品使用声明 质量保证 Evaluated by Western Blotting in human brain tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected GARS in 30 µg of human brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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