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merck millipore,默克密理博,MABN763,Anti-Ubiquilin 2 Antibody, clone 6H9
产品名称：Anti-Ubiquilin 2 Antibody, clone 6H9
产品型号：MABN763
Detect Ubiquilin-2 using this mouse monoclonal antibody, Anti-Ubiquilin 2 Antibody, clone 6H9 validated for use in western blotting & ICC.
merck millipore,默克密理博,MABN763,Anti-Ubiquilin 2 Antibody, clone 6H9
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H ICC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN763 描述 Anti-Ubiquilin 2 Antibody, clone 6H9 Alternate Names - Ubiquitin-like product Chap1/Dsk2
- Ubiquilin-2
- Chap1
- DSK2 homolog
- Protein linking IAP with cytoskeleton 2
- PLIC-2
- hPLIC-2
背景信息 Ubiquilin-2, also known as Chap1, DSK2 homolog, Protein linking IAP with cytoskeleton 2 (PLIC-2 or hPLIC-2), Ubiquitin-like product Chap1/Dsk2, and encoded by the gene UBQLN2/N4BP4/PLIC2, is a protein that appears to modulate the half-life of proteins destined to be degraded by the proteasome. Ubiquilin 2 binds UBE3A and BTRC ubquitin ligases and interacts with the 19S proteasome subunit to mediate its activity. Ubiquilin 2 is localized to the cytoplasm and nucleus, and colocalizes with proteasome. Ubiquilin 2 is expressed in mitotic cells very strongly; expression is low in non-dividing cells. Defects in Ubiquilin 2 may be associated with ALS form 15 a neurodegenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord, resulting in fatal paralysis. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ other in buffer containing PBS with 0.05% sodium azide. 应用 应用 Detect Ubiquilin-2 using this mouse monoclonal antibody, Anti-Ubiquilin 2 Antibody, clone 6H9 validated for use in western blotting & ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Western Blotting Analysis: 1.0 µg/mL from a representative lot detected Ubiquilin 2 in 10 µg of SH-SY5Y and NIH-3T3 cell lysate.
Immunocytochemistry Analysis: A representative lot detected Ubiquilin 2 in HeLa cells.生物信息 免疫原品种 Recombinant protein corresponding to human Ubiquilin 2. 克隆 6H9 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 MouseHuman Species Reactivity Note Human, Mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_038472
基因符号 - PLIC2
- UBQLN2
- N4BP4
纯化方法 Protein G purified UniProt编号 - Q9UHD9
产品使用声明 质量保证 Evaluated by Western Blotting in U-251 cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Ubiquilin 2 in 10 µg of U-251 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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